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abrupt increases in fasting levels of plasma glucose concentrations between 5 and 9 AM, in the absence of antecedent hypoglycemia; occurs in diabetic patients receiving insulin therapy.
Etymology: ME, daunen + Gk, phainomenon, anything seen
a tendency for persons with type 1 diabetes mellitus to experience hyperglycemia upon awakening in the morning because of increased cortisol and growth hormone secretion in the predawn hours. Compare Somogyi effect (phenomenon).
dawn phenomenonDiabetology Early morning hyperglycemia not preceded by hypoglycemia, linked to ↑ insulin requirements in type 1 DM, possibly due to nocturnal pulses of hGH; DP also occurs in insulin-pump users receiving continuous subcutaneous insulin infusion, who are presumed to be euglycemic; DP is attributed to residual endogenous insulin or insulin-like molecules. Cf Somogyi phenomenon, Subcutaneous insulin resistance syndrome.
dawn phe·nom·e·non(dawn fĕ-nom'ĕ-non)
Abrupt increases in fasting levels of plasma glucose concentrations between 5-9 am in the absence of antecedent hypoglycemia; occurs in diabetic patients receiving insulin therapy.