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daunorubicin |
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daunorubicin /dau·no·ru·bi·cin/ (daw?no-roo´bi-sin) an anthracycline (q.v.) antibiotic used as an antineoplastic; administered as the hydrochloride salt or as a liposome-encapsulated preparation of the citrate salt. daunorubicin an anthracycline antibiotic produced by a strain of Streptomyces coeruleorubidus that is closely related to doxorubicin and has antimitotic, cytotoxic and immunosuppressive effects. |
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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. The liposomal anthracyclines (liposomal daunorubicin and pegylated liposomal doxorubicin) have mild myelotoxicity at the doses used in KS, and in general can be used even with myelotoxic antiretroviral drugs such a zidovudine, when necessary. He was placed on a chemotherapeutic regimen of daunorubicin and cytosine arabinoside (ARA-C) for remission induction of AML. |
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daunorubicin
