dapsone


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dapsone

 [dap´sōn]
an antibacterial used in treatment of leprosy and dermatitis herpetiformis and for prophylaxis of malaria caused by Plasmodium falciparum. Called also DDS.

dap·sone

(dap'sōn),
An antibiotic used to treat leprosy and certain cutaneous diseases such as dermatitis herpetiformis, is active against the tubercle bacillus, is used in the treatment of bovine coccidiosis and streptococcal mastitis, and is used as a second-line agent in Pneumocystis jiroveci [carinii] pneumonia.

dapsone

/dap·sone/ (dap´sōn) an antibacterial bacteriostatic for a broad spectrum of gram-positive and gram-negative organisms; used as a leprostatic, as a dermatitis herpetiformis suppressant, and in the prophylaxis of falciparum malaria.

dapsone

(dăp′sōn′, -zōn′)
n.
A sulfone drug, C12H12N2O2S, that is used primarily to treat leprosy and some forms of dermatitis.

dapsone (DDS)

[dap′sōn]
a bacteriostatic and bactericidal sulfone derivative.
indications It is prescribed in the treatment of leprosy and dermatitis herpetiformis and for prophylaxis against toxoplasmosis and Pneumocystis carinii in immunocompromised patients.
contraindications Known hypersensitivity to this drug prohibits its use. It is not recommended for use during pregnancy or lactation.
adverse effects Among the more serious adverse reactions are hemolysis (particularly in people who have glucose-6-phosphate dehydrogenase deficiency), leprosy reactional state, methemoglobinemia, neuropathy, nausea, anorexia, toxic hepatic aplastic anemia, and skin rash. Dapsone was carcinogenic in animal models.

dap·sone

(dap'sōn)
An antibiotic used to treat leprosy and cutaneous diseases such as dermatitis herpetiformis; active against the tubercle bacillus; used in the treatment of bovine coccidiosis and streptococcal mastitis and as a second-line agent in Pneumocystis jiroveci [carinii] pneumonia.

dapsone

Diaminodiphenyl sulfone. For many years this has been the standard drug to treat leprosy, but irregular use has led to the development of drug resistance. Dapsone is also used in the treatment of DERMATITIS HERPETIFORMIS which may be associated with COELIAC DISEASE.

dap·sone

(dap'sōn)
Antibiotic used to treat leprosy; active against the tubercle bacillus; used as a second-line agent in Pneumocystis jiroveci (carinii) pneumonia.

dapsone (DDS)

(dap´sōn),
n brand name: Avlosulfon;
drug class: leprostatic, antibacterial;
action: bactericidal and bacteriostatic against
M. leprae; may also be immunosuppressant;
uses: leprosy and dermatitis herpetiformis.

dapsone

an antibacterial used in humans for the treatment of leprosy and malaria. Used in cats to treat mycobacterial infections, particularly feline leprosy, caused by Mycobacterium lepraemurium.
References in periodicals archive ?
There are many different protocols assessing efficacy or "success" in acne trials, so it's difficult to say exactly how dapsone compares in efficacy with other products on the market, Dr.
In any event, there can be no assurance that dapsone, or any other compound currently being evaluated by Immune Network, can be adapted for use as an effective and commercially viable treatment for Alzheimer disease.
The efficacy and tolerability of dapsone 5% gel in female vs male patients with facial acne vulgaris: Gender as a clinically relevant outcome variable.
10 A study was carried out by Elgart, that included four patients with pyoderma gangrenosum unresponsive to treatment with prednisone, cyclosporin, colchicine, cytoxan, and dapsone.
ulcerans before his arrival in the Netherlands in 1977, it is unlikely that the dapsone and clofazimine that he received for treatment of leprosy could have controlled the infection.
Wardekar (4) reported results from two surveys, but only those 0-25 years of age were allocated to receive dapsone or a placebo, and thus, only this age group was used to estimate the effects of the chemoprophylaxis.
Liver P-450 enzymes catalyze conversion of dapsone to N-hydroxy-dapsone.
Treatment with tetracyclines was discontinued and dapsone was introduced in a 100 mg daily dose.
The patient was prescribed dapsone and advised to take it for 2 years.
Dapsone was the most common adjuvant therapy employed followed by tetracyclines.
Dapsone (diamino-diphenyl sulfone, DDS) is used clinically in humans to treat several dermatological conditions, specifically those related to inflammatory diseases, autoimmune dermatoses and illnesses that involve neutrophil infiltration of the skin such as dermatitis herpetiformis and Sweet syndrome.
3), reported a clinical case with good response and lack of recurrence with combined therapy of 80 mg of isotretinoin plus 100 mg of dapsone daily and then maintenance therapy with 50 mg of dapsone interdaily.