danaparoid


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danaparoid

 [dah-nap´ah-roid]
an agent used as the sodium salt in prophylaxis of pulmonary thromboembolism and deep venous thrombosis.

danaparoid

/da·nap·a·roid/ (dah-nap´ah-roid) an antithrombotic used as the sodium salt in the prophylaxis of pulmonary thromboembolism and deep venous thrombosis.

danaparoid

an anticoagulant.
indications It is used to prevent vein thrombosis in hemodialysis, stroke, elective surgery for malignancy or total hip replacement, and hip fracture surgery.
contraindications Hypersensitivity to this drug, sulfites, or pork products prohibits its use. Other factors that contraindicate its use include hemophilia, leukemia with bleeding, thrombocytopenia, purpura, cerebrovascular hemorrhage, cerebral aneurysm, severe hypertension, and other severe cardiac disease.
adverse effects Life-threatening side effects include hemorrhage and thrombocytopenia. Hypersensitivity reactions and rash are additional adverse effects.

danaparoid

Orgaran® Cardiovascular disease An injectable, LMW heparin that ↓ risk of postop DVT and PE after hip replacement surgery; it is also used for heparin-induced thrombocytopenia. See Deep vein thrombosis, Heparin-induced thrombocytopenia, Pulmonary embolism.
References in periodicals archive ?
Danaparoid was used previously with success, but this product is no longer available.
The present in vitro experiments were planned to determine whether the DTIs lepirudin and argatroban and the predominantly factor Xa inhibitors enoxaparin, danaparoid, and fondaparinux could interfere with the result of LA testing based on dPT.
He was infused large-volume crystalloid fluids and diuretics for HC along with danaparoid for prevention of clots in the bladder, but his hematuria progressed to grade IV and MGH from day 17.
Heparin-induced thrombocytopenia--therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes.
Bu durumda antikoagulan tedavi seceneklerini danaparoid, lepuridin, argatroban ve bir sentetik dusuk molekul agrilikli heparin (DMAH) olan fondaparinux olusturur [4].
The team then decided to trial danaparoid sodium (Danaparoid), a low-molecular weight (LMW) heparin, chemically distinct from heparin.
Heparine bagli trombositopeni gelisen hastalarda KPB sirasinda antikoagulasyon icin danaparoid, ancrod ve recombinant hirudin tercih edilebilir.
Danaparoid, a low-molecular-weight heparinoid with low placental permeability, is considered by some to be the drug of choice for heparin allergy in pregnancy, (12,17-19) but is currently not available in South Africa and was therefore not an option in this patient.
Christin F, Theissen-Laval O, Loeb JP Danaparoid (orgaran) for continuous venovenous hemodiafiltration in a patient with heparin-induced thrombocytopenia.
Other anticoagulants not available in the local setting include the direct thrombin antagonist, argatroban, and the heparinoid danaparoid.
The three available LMWH products, dalteparin (Fragmin), enoxaparin (Lovenox), and tinzaparin (Innohep), and a low-molecular-weight heparinoid, danaparoid, are rated B, because animal reproduction studies have found no evidence of fetal harm.
College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: the clinical use and laboratory monitoring of low-molecular-weight heparin, danaparoid, hirudin and related compounds, and argatroban.