dalfopristin

dalfopristin

 [dal-fo´pris-tin]
a semisynthetic antibacterial effective against a variety of gram-positive organisms. It is used in conjunction with quinupristin in the treatment of serious bacteremia caused by vancomycin-resistant Enterococcus faecium and complicated skin and skin structure infections caused by Streptococcus pyogenes or methicillin-sensitive Staphylococcus aureus; administered intravenously.

dalfopristin

/dal·fo·pris·tin/ (dal-fo´pris-tin) a semisynthetic antibacterial used in conjunction with quinupristin against various gram-positive organisms, including vancomycin-resistant Enterococcus faecium.

dalfopristin

[dalfo′pristin]
a semisynthetic antibacterial effective against a variety of gram-positive organisms. It is used in conjunction with quinupristin in the treatment of serious bacteremia caused by vancomycin-resistant Enterococcus faecium and complicated skin and skin structure infections caused by Streptococcus pyogenes or methicillin-sensitive Staphylococcus aureus; it is administered intravenously.

dalfopristin

See Synercid®.
References in periodicals archive ?
8) dalfopristin Antibiotic VSE (N = 20), n (%) Susceptible Intermediate Resistant Erythromycin 12 (60) 6 (30) 2 (10) Ampicillin 9 (45) 6 (30) 5 (25) Vancomycin 20 (100) -- -- Teicoplanin 20 (100) -- -- Tetracycline 10 (50) 2 (10) 8 (40) Doxycycline 16 (80) 1 (5) 3 (15) Ciprofloxacin 7 (35) 4 (20) 9 (45) Levofloxacin 11 (55) 2 (10) 7 (35) Nitrofurantoin 20 (100) -- -- Rifampicin 2 (10) 9 (45) 9 (45) Linezolid 20(100) -- -- Tigecyclin 20 (100) -- -- Quinupristin/ 8 (40) 5 (25) 7 (35) dalfopristin
Tn5406, a New Staphylococcal Transposon Conferring Resistance to Streptogramin A and Related Compounds Including Dalfopristin.
AMP--ampicillin, IMP--imipenem, VA--vancomycin, LZD--linezolid, QD--quinupristin/ dalfopristin, SXT--trimethoprim/sulfamethoxazole, TGC--tigecycline.
For patients who have recently suffered from infection with vancomycin resistant Enterococcus (VRE) or MRSA, prophylaxis with linzolid, or quinupristin / dalfopristin can be considered.
Treatment of hospitalized patients with complicated gram-positive skin and skin structure infections: Two randomized, multicentre studies of quinupristin/ dalfopristin versus cefazolin, oxacillin or vancomycin.
Vancomycin, linezolid, gentamicin, moxifloxacin, quinupristin/ dalfopristin, and rifampicin were 100% effective (susceptible).
Concentracion Inhibitoria Minima Cepas de SCN Quinopristin / dalfopristin ([micro]g/mL) Numero Porcentaje 0.
The dalfopristin component interferes with early phases of bacterial protein synthesis and quinipristin interferes with the late phase of protein synthesis.
Based on the Naranjo probability scale, the likelihood that quinupristin dalfopristin caused the anemia and reticulocytopenia is probable.
Treatment of methicillin - resistant Staphylococcus aureus infections with quinupristin - dalfopristin in patients intolerant of or failing prior therapy.
5 mg/kg BID Vancomycin- dalfopristin resistant enterococci Linezolid 7.
Although, as a streptogramin B, quinupristin is cross-resistant with macrolides and lincosamides, dalfopristin is a streptogramin A and not part of this resistance pattern.