dactinomycin /dac·ti·no·my·cin/ (dak″tĭ-no-mi´sin) actinomycin D, an antibiotic derived from several species of Streptomyces; used as an antineoplastic.
dactinomycin
dactinomycin [dak″tĭ-no-mi´sin]
dactinomycin
dac·ti·no·my·cin (d k t -n -m  sn)n. An antibiotic isolated from bacteria and used as an antineoplastic agent in the treatment of certain cancers. |
dactinomycin
[dak′tinōmī′sin]
an antibiotic used as an antineoplastic agent.
indications It is prescribed in the treatment of a variety of malignant neoplastic diseases, including testicular cancer, melanoma, Wilms' tumor, and rhabdomyosarcoma.
contraindications Herpes zoster infection, chickenpox, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are bone marrow depression, severe GI disturbances, proctitis, alopecia, and ulcers of the mouth.
dactinomycin [dak″tĭ-no-mi´sin]
an antitumor antibiotic of the actinomycin complex (actinomycin D), produced by Streptomyces parvulus. Used to treat rhabdomyosarcoma and Wilms' tumor in children, as well as Ewing's sarcoma, Kaposi's sarcoma, osteogenic sarcoma, soft tissue sarcomas, testicular carcinoma, and choriocarcinoma.
dactinomycin
an antibiotic of the actinomycin complex (actinomycin D), produced by several species of Streptomyces; used as an antineoplastic agent.
dactinomycin
Oncology An antitumor antibiotic member of a class of drugs first isolated from Streptomyces, and used to treat Wilms' tumor, Ewing sarcoma, embryonal rhabdomyosarcoma, choriocarcinoma, seminoma, KS, lymphoma
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