ELP4

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ELP4

A gene on chromosome 11p13 that encodes a widely expressed protein which acts as a subunit of the RNA polymerase-II elongator complex, a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme involved in transcriptional elongation. The elongator complex acetylates histone H3 and possibly also H4, and it may play a role in chromatin remodelling.