d-isomer

d-isomer,

n a stereo-iso-mer whose asymme-tric carbon atom rotates plane-polarized light clockwise. See also asymmetric carbon atom.
References in periodicals archive ?
It is constituted by a 50/50 combination of two isomers: an l-isomer that is a potent opioid agonist, and a d-isomer that has virtually no opioid activity at the proposed doses and that has also been shown to possess NMDA antagonist properties.
d-Methadone is a d-isomer of methadone but, unlike the parent molecule, inhibits pain through antagonism at the NMDA receptor, is substantially devoid of opioid activity and should enter Phase II in H116.
L-Carnipure is Lonza's 100% guaranteed pure, natural L-carnitine, and does not contain the harmful D-isomer.
Dextromethorphan is a prodrug converted to the D-isomer of levorphanol, a semisynthetic morphine derivative, which noncompetitively antagonizes N-methyl-D-aspartate (NMDA) receptors, and possibly also affects serotonin receptors.
JAMA, 1986), only the L-isomer is available, with the D-isomer (if found in commercial L-carnitine supplies) being present in trace quantities that have yet to be shown to be biologically undesirable in vivo.
The l-isomer is a potent opioid agonist, whereas the d-isomer has virtually no opioid activity at the proposed doses and has also been shown to possess NMDA antagonist properties.
Nagase's unnatural amino acids include not only D-isomer amino acids but a variety of alpha Methyl substituted L- and D-amino acids.
Focalin is an advance in single-isomer technology and is formulated by isolating the active d-isomer of methylphenidate.
FOCALIN XR is an advance in single-isomer technology and is formulated by isolating the active d-isomer of methylphenidate, providing favorable tolerability and dosing flexibility at only half the dose.
Focalin contains only the d-isomer, which is responsible for the effective management of the symptoms of ADHD.
Focalin(TM) (dexmethlyphenidate hydrochloride) containing only the effective d-isomer, is a refined form of Ritalin(R) (d,l-thero-methlyphenidate hydrochloride), which provides similar efficacy and a favorable side effect profile at half the Ritalin milligram dosage.
Snyder, discovered that the D-isomer of the amino acid, serine (D-serine), was the principal activator of this site.