cytotrophoblast


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cytotrophoblast

 [si″to-trof´o-blast]
the cellular (inner) layer of the trophoblast.

cy·to·tro·pho·blast

(sī'tō-trof'ō-blast),
The inner cellular layer of the trophoblast of a blastocyst.
Synonym(s): Langhans layer

cytotrophoblast

/cy·to·tro·pho·blast/ (-tro´fo-blast) the cellular (inner) layer of the trophoblast.cytotrophoblas´tic

cytotrophoblast

[sī′tōtrof′əblast′]
Etymology: Gk, kytos + trophe, nutrition, blastos, germ
the inner layer of cells of the trophoblast of the early mammalian embryo that gives rise to the outer surface and villi of the chorion. Also called Langhans' layer. Compare syncytiotrophoblast. cytotrophoblastic, adj.

cy·to·tro·pho·blast

(sī'tō-trō'fō-blast)
The inner cellular layer of the trophoblast.

Langhans,

Theodor, German pathologist, 1839-1915.
Langhans cells - multinucleated giant cells seen in tuberculosis and other granulomas. Synonym(s): cytotrophoblastic cells; Langhans-type giant cells
Langhans layer - the inner layer of the trophoblast. Synonym(s): cytotrophoblast
Langhans stria - fibrinoid that accumulates on the chorionic plate between the bases of placental villi during the first half of pregnancy.
Langhans-type giant cells - Synonym(s): Langhans cells

cytotrophoblast

the cellular (inner) layer of the trophoblast.
References in periodicals archive ?
2011) and has a dose-dependent effect upon apoptosis of primary human cytotrophoblast cells via tumor necrosis factor-a (Benachour and Aris 2009).
The thickness of cytotrophoblast and syncytiotrophoblast considerably varies narrowing in the area of fetal blood vessels.
Cytogenetic studies of the placenta showed that the mesenchymal core had a 46,XX karyotype and the cytotrophoblast layer was 45,X.
47) Heterogeneous placental hypermaturity, with only focally increased villous vascularity, villous cytotrophoblast density, Hofbauer cells, and nonapoptotic syncytial knotting, and a decreased extracellular matrix of chorionic villi are the characteristic features.
Th2 type cytokines, such as IL-10, are anti-inflammatory cytokines, and act as autocrine inhibitors of cytotrophoblast invasion in the uterine wall.
Hyperglycosylated hCG, which is an hCG variant with additional carbohydrate residues that is produced by cytotrophoblast cells, (4) is the principal molecule produced in early pregnancy.
Viral antigens were present in the maternal pulmonary system, and virus was detected in placental Hofbauer cells (histiocytes), cytotrophoblast, fetal lung, circulating mononuclear cells, and liver macrophages (10).
Excess soluble VEGFR-1 (a product of alternative splicing of VEGFR-1 also referred to as sVEGFR-1 or sFLT-1) inhibits placental cytotrophoblast differentiation and invasion and contributes to the abnormal placentation associated with preeclampsia.
The cytotrophoblast separates both the circulations and extends into the decidua basalis to form villi.
Impaired Cytotrophoblast Cell--Cell Fusion Is Associated with Reduced Syncytin and Increased Apoptosis in Patients with Placental Dysfunction," Molecular Reproduction and Development 75 (2008): 175-83; K.
However, as in normal placenta, the cytotrophoblast cells and intervillous cells were devoid of the enzyme activity.
Expression of the genes for 3p-hydroxysteroid dehydrogenase type 1 and cytochrome P450scc during syncytium formation by human placental cytotrophoblast cells in culture and the regulation by progesterone and estradiol.