cytotoxic drug


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cytotoxic drug

any pharmacological compound that inhibits the proliferation of cells within the body. Such compounds as the alkylating agents and the antimetabolites designed to destroy cells (with a high growth fraction) are commonly used in chemotherapy. Cytotoxic agents have a potential for producing teratogenesis, mutagenesis, and carcinogenesis.

cytotoxic drug

Oncology An anticancer drug which acts by killing or preventing the cell division Adverse effects Damage to noncancerous tissues or organs with a high proportion of actively dividing cells–eg, BM, hair follicles, GI tract, thereby limiting the amount and frequency of drug administration. See Chemotherapy.
References in periodicals archive ?
And instilling cytotoxic drugs directly into these cavities is an option, but not widely used because of the high risk of damage to healthy tissues.
using a least hazardous cytotoxic drug to achieve the desired therapeutic benefit
He also will oversee the company's potent and cytotoxic drug development services, which include a dedicated and segregated potent facility.
ADCs are composed of an antibody linked to cytotoxic drugs, whereby the antibody part specifically targets and delivers the cytotoxic drug to cancer cells which could lead to higher drug levels at the tumor site.
The monoclonal antibody portion binds PSMA with high affinity and specificity, thereby targeting the cytotoxic drug to cancer cells.
In this role, she conducted many breast cancer treatment clinical trials, including evaluation of high-dose chemotherapies and hematopoietic growth factors, new cytotoxic drug combinations, novel hormonal treatments, monoclonal antibody and gene therapies for breast cancer.
Preparations for cytotoxic drugs synonymous must come from the list of reimbursed medicines.
2, 2014 /PRNewswire/ -- The 'HPAPIs and Cytotoxic Drugs Manufacturing Market, 2014-2024' report provides an extensive study of the rapidly growing manufacturing market of HPAPIs and cytotoxic drugs.
Such recommendations include guidelines on safe handling of cytotoxic drugs published by the Government of South Australia in 2012.
Three-year supply of medical devices for the preparation of cytotoxic drugs to the pharmacy unit of the University Hospital Policlinico "Paolo Giaccone" - code 4241387 race.
Emerging treatment options include new cytotoxic drugs, new targeted therapies and new biological treatments, which include gene therapy.
Supply three-year, in separate batches, complete sets for multiple administration of cytotoxic drugs to the needs of AUSL Bologna and Imola, osped Enterprises.

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