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cytotoxic drug |
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cytotoxic drug, any pharmacologic compound that inhibits the proliferation of cells within the body. Such compounds as the alkylating agents and the antimetabolites designed to destroy cells (with a high growth fraction) are commonly used in chemotherapy. Cytotoxic agents have a potential for producing teratogenesis, mutagenesis, and carcinogenesis. cytotoxic drug Oncology An anticancer drug which acts by killing or preventing the cell division Adverse effects Damage to noncancerous tissues or organs with a high proportion of actively dividing cells–eg, BM, hair follicles, GI
tract, thereby limiting the amount and frequency of drug administration. See Chemotherapy. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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One of the alarming admissions was that this cytotoxic drug had found its way back into use without the knowledge of chiefs of nursing or medicine. Today, we use both a steroid and a cytotoxic drug as an initial treatment for a high percentage of our patients, as we will report in a future publication. The monoclonal antibody portion binds PSMA with high affinity and specificity, thereby targeting the cytotoxic drug to cancer cells. |
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