cytotoxic T-cell


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cytotoxic T-cell

a specialized T-cell which recognizes and destroys infected body cells during a cell-mediated immune response.
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But getting the best cytotoxic T-cell response and incorporating it into off-the-shelf vaccines are only half the battle, Dr.
Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma: [CD3.
An ultrastructural study of cutaneous panniculitis-like T-cell lymphoma: cytoplasmic granules and active cellular and cell-to-matrix interaction mimic cytotoxic T-cells.
Once the epitope candidates selected by this method are confirmed in cytotoxic T-cell (CTL) assays, they may be useful for 1) screening exposed persons for T-cell responses, 2) investigating the immunopathogenesis of WN virus disease in humans, 3) as components of diagnostic kits developed for WN virus surveillance, 4) as reagents for measuring WN virus vaccine-related immune responses, and possibly 5) as components of a subunit vaccine for WN virus.
Poly-ICR is a Toll-like Receptor 3 (TLR3) agonist that when combined with a disease-specific antigen can induce both cytotoxic T-cell and antibody (B-cell) immune responses against that antigen.
Acemannan acts on cells in the immune system that release Tumor Necrosis Factor (TNF), Interleukin-1 (IL-1), Interleukin-6 (IL-6), triggers an increase in natural killer cell and cytotoxic T-Cell activity, potentiates cellular and humoral immunity, and increases the natural healing process.
Acemannan stimulates macrophage to release Tumor Necrosis Factor (TNF), Interleukin-1 (IL-1) and Interleukin-6 (IL-6), triggers an increase in natural killer cell and cytotoxic T-Cell activity, potentiates cellular and humoral immunity and increases macrophage release of Nitric Oxide (NO) that contribute to tumor breakdown.
Blood cells from four of these patients were pulsed (immunised ex vivo) with GV1001 and generated cytotoxic T-cell (CTL's).
Furthermore, recent evidence suggests cytotoxic T-cell lymphocytes (CTL) are important for induction and maintenance of the disease-free status of LTNP.
The most reactive Ii-Key/melanoma peptides from gp100 and tyrosinase will be tested in combination with corresponding cytotoxic T-cell stimulating peptides, which have been used previously in the clinic.
In building on the success of our first melanoma trial, we have developed a second generation Javelin(TM) technology that gives an approximately ten- fold increase in cytotoxic T-cell responses in animal models," commented Dr.
The allowed claims, from an application entitled "Identification of Broadly Reactive DR Restricted Epitopes," extend the patent coverage of previously issued patents covering HLA class I immune receptors and cytotoxic T-cell epitopes to now include HLA class II immune receptors and helper T-cell epitopes.

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