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cytotoxic T lymphocyte |
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cytotoxic having a deleterious effect upon cells. cytotoxic antibody see cytotoxic antibody. cytotoxic drugs generally refers to those used in chemotherapy of neoplasms, e.g. cyclophosphamide, vincristine, etc. cytotoxic T lymphocyte see T lymphocyte. cytotoxic T lymphocyte CTL, cytotoxic T cell Immunology A subset of T cells with a CD8 receptor on the surface that recognizes and lyses malignant or virally-infected self cells bearing self, ie 'haplotype restricted', class I MHC
molecules. See Helper cells, Perforin, Suppressor cells. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In addition to stimulating B lymphocytes, Th2 cells suppress the cytotoxic T lymphocyte response, decreasing the robustness of cell-mediated immunity. Induction of cytotoxic T lymphocyte development from murine thymocytes by IL-1 and IL-6. In addition, each antigen fragment is fused to the ubiquitin protein to increase antigen expression and target these antigens to the proteasome to enhance cytotoxic T lymphocyte (CTL) responses. |
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