cytotoxic T cell


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cytotoxic T cell

cytotoxic T cell

See CD8 cell.

cytotoxic T cell

A CD8+ T lymphocyte that can destroy microorganisms directly through the release of perforin and proteolytic enzymes. These cells are particularly important in the defense against viruses, rejection of allografts, and, possibly, new malignant cells. Synonym: CD8 cell; cytotoxic cel; killer T cell
See also: cell
References in periodicals archive ?
The demonstration that infused cytotoxic T cells can migrate to lymph nodes, the major site of HIV-1 replication -- and that this is associated with greater cytotoxic activity against HIV-1 in the lymph nodes -- provides hope that this form of therapy may benefit HIV-1 infected persons.
The cells then transport the combination to the cell surface so that cytotoxic T cells can have access to them.
IL-21 has potent biological activity in regulating key classes of immune cells, including cytotoxic T cells and natural killer cells.
IL-21, a protein discovered through ZymoGenetics' genomic research efforts, stimulates the proliferation and activation of natural killer cells and cytotoxic T cells, cell types involved in the destruction of cancerous and infected cells.
IDM elected to exercice its option to license a selection of epitopes based on the results of its preclinical studies designed to evaluate the stimulation of specific cytotoxic T cells (CTL's) using peptide loaded dendritic cells.
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