cytotoxic T cell


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cytotoxic T cell

cytotoxic T cell

See CD8 cell.

cytotoxic T cell

A CD8+ T lymphocyte that can destroy microorganisms directly through the release of perforin and proteolytic enzymes. These cells are particularly important in the defense against viruses, rejection of allografts, and, possibly, new malignant cells. Synonym: CD8 cell; cytotoxic cel; killer T cell
See also: cell
References in periodicals archive ?
Doherty notes that investigators are now using cytotoxic T cells to rid bone marrow transplants of viral infections and are designing vaccines, including those for AIDS, to generate these virus-killing cells.
IL-21, a protein discovered through ZymoGenetics' genomic research efforts, stimulates the proliferation and activation of natural killer cells and cytotoxic T cells, cell types involved in the destruction of cancerous and infected cells.
IDM elected to exercice its option to license a selection of epitopes based on the results of its preclinical studies designed to evaluate the stimulation of specific cytotoxic T cells (CTL's) using peptide loaded dendritic cells.
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