cytotoxic


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cytotoxic

 
having destructive action on cells, usually only certain types of cells; see cytotoxicity.

cy·to·tox·ic

(sī'tō-tok'sik),
Detrimental or destructive to cells.

cytotoxic

(sī′tə-tŏk′sĭk)
adj.
Of, relating to, or producing a toxic effect on cells.

cy′to·tox·ic′i·ty (-tŏk-sĭs′ĭ-tē) n.

cytotoxic

See cytotoxin.

cy·to·tox·ic

(sī'tō-tok'sik)
Detrimental or destructive to cells; pertaining to the effect of noncytophilic antibody on specific antigen, frequently, but not always, mediating the action of complement.

cytotoxic

cell-destructive, e.g. antibody-antigen reaction, usually involving complement activation

cy·to·tox·ic

(sī'tō-tok'sik)
Detrimental or destructive to cells.

cytotoxic

having a deleterious effect upon cells.

cytotoxic antibody
see cytotoxic antibody.
cytotoxic drugs
generally refers to those used in chemotherapy of neoplasms, e.g. cyclophosphamide, vincristine, etc.
cytotoxic T lymphocyte
see T lymphocyte.
References in periodicals archive ?
Prime screening of the extract through cytotoxic activity provides useful information about the antitumor and anticancer activity for the future use of the medicinal plants extract.
Our approved Safebridge Category 4, GMP facility in Lugano was designed to accommodate the complex processes needed for production of very potent active ingredients including cytotoxics like ADCs.
The report reviews Cytotoxic T-Lymphocyte Protein 4 (CTLA-4 or CD152) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Further, patient-derived bacteria and cells can be co-cultured in the presence of various antibiotics to determine whether antibiotic treatment blocks the cytotoxic activity of the isolate.
Native PAGE of the chromatographic fractions from the last column chromatography showed only one band, indicating that the cytotoxic factor was electrophoretically purified.
We are focusing on Disorazol Z," Sachse explained, "because it is an ideal compound for the formation of cytotoxic conjugates with peptides, proteins and antibodies to selectively target cancer cells.
8220;It also should help CMOs make strategic investment decisions when it comes to producing cytotoxic injectable drugs.
Protective clothing must be worn by all personnel preparing cytotoxic drugs, cleaning cytotoxic preparation facilities, or cleaning cytotoxic spills.
Results: Data on cytotoxic effects could be obtained from primary cultures in 18 of the 27 recruited patients.
A 1996 study published in the Archives of Environmental Health found that the cytotoxic drug methotrexate was present in urine samples of nurses who'd been caring for chemotherapy patients.
Procedures that govern the use of cytotoxic medications for oncology indications are also applicable when medications such as cyclophosphamide are used for non-oncology purposes.