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cytosine |
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cytosine /cy·to·sine/ (si´to-sēn) a pyrimidine base occurring in animal and plant cells, usually condensed with ribose or deoxyribose to form the nucleosides cytidine and deoxycytidine, major constituents of nucleic acids. Symbol C. cytosine arabinoside cytarabine.
cytosine [sī′təsin] a pyrimidine base that is a component of DNA and RNA. In free or uncombined form it occurs in trace amounts in most cells, usually as a product of the enzymatic hydrolysis of nucleic acids and nucleotides. On hydrolysis, it is converted to urea and ammonia. See also thymine, uracil. cytosine a pyrimidine base found in the nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). cytosine arabinoside see cytarabine. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| A substitution of cytosine for guanine, also located in VD 1, resulted in Gln instead of Glu at amino acid position 117, as found in genotype B and strain 6BC (numbering according to the ompA amino acid sequence of the C. Intended as a research tool, the T790M quantitative mutation assay detects the presence of a mutant thymidine base in a background of normal cytosine bases at position 2369 of the EGFR gene. Methylation of cytosines in cytosine--guanine (CpG) dinucleotides represents a critical epigenetic DNA modification affecting gene expression and cellular function (Bird 2002). |
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