Ohno-Iwashita, Interaction of Theta-Toxin (Perfringolysin O), a Cholesterol-Binding Cytolysin
, with Liposomal Membranes: Change in the Aromatic Side Chains Upon Binding and Insertion, Biochem.
Menestrina (2001) Effects of lipid composition on membrane permeabilization by Sticholysin I and II, two cytolysins
of the sea anemone Stichodactyla helianthus.
2003) has suggested that cytolysin
production ((3 hemolysis) is widespread among enterococci.
Vibrio cholerae cytolysin
is essential for high enterotoxicity and apoptosis induction produced by a cholera toxin gene-negative V.
Pleurotolysin, a novel sphingomyelin-specific two-component cytolysin
from the edible mushroom Pleurotus ostreatus, assembles into a transmembrane pore complex.
Shvets (1998): <<Low-molecular cytolysins
and trypsin inhibitors from sea anemone Radianthus macrodactylus.
Sword and shield: linked group B streptococcal beta-hemolysin/ cytolysin
and carotenoid pigment function to subvert host phagocyte defense.
SLO is an important GAS cytolysin
that enhances cytotoxicity and toxin translocation (34,35), and its heightened expression would be expected to increase virulence.
metschnikovii produces a cytolysin
with hemolytic properties (10).
These findings suggest that neither metalloprotease nor cytolysin
is essential for the virulence or invasiveness of V.
Characterization of anthrolysin O, the Bacillus anthracis cholesterol-dependent cytolysin
Moreover, STEC strains almost invariably harbor a 97-kb plasmid encoding possible additional virulence traits such as STEC hemolysin (which acts as a pore-forming cytolysin
on eukaryotic cells ); the bifunctional catalase peroxidase KatP (8); a secreted serine protease (espP, which can cleave human coagulation factor V ); and the etpD gene cluster (which probably encodes a type II secretion pathway [10, 11]).