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cytokinesis |
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cytokinesis /cy·to·ki·ne·sis/ (si″to-ki-ne´sis) the division of the cytoplasm during the division of eukaryotic cells.
cytokinesis [sī′tōkinē′sis, -kīnē′sis] Etymology: Gk, kytos + kinesis, movement the division of the cytoplasm, exclusive of nuclear division, that occurs during the final stages of mitosis and meiosis to form daughter cells. See also karyokinesis. cytokinetic, adj. cytokinesis How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| After 44 hr of incubation, cytochalasin-B (Sigma) was added to the culture medium at a final concentration of 6 [micro]g/mL to arrest cytokinesis. Its cellular mode of action against proliferating cells was consistent with Aurora A and B modulation as it inhibited histone H3 phosphorylation, slowed entry into mitosis, blocked cytokinesis and caused polyploidy. The frequency of micronuclei (MN) in peripheral blood lymphocytes determined with the cytokinesis block assay is among the most popular biomarkers used for this purpose, although large inter- and intralaboratory variability of this end point has been observed in population studies. |
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