cytokine network

cytokine network

a group of cytokines that together modulate and regulate key cellular functions.

cytokine network

a group of cytokines that modulate and regulate signaling between cells during immune responses. According to the immune network model, T cells and B cells mutually interact, responding to cytokines as well as antigens. This interaction allows the cytokines to direct T cells to antiviral or antitumor functions or to promote allergic reactions.
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The aim of this study was to explore the frequency and function of pDC and serum cytokine network profiles in patients with acute or chronic HBV infection.
3] Studies have shown resemblance of the cytokine network in schizophrenia to a state of acute stress, in which proinflammatory cytokines, such as Interleukin-1[alpha] (IL-1[beta]) and tumor necrosis factor-[alpha] (TNF-[alpha]), were elevated.
The company leverages its world class expertise in cytokine biology, originating in research conducted at the National Institutes of Health, to develop a novel approach to selectively inhibit functionally redundant cytokines while leaving the rest of the cytokine network intact.
In previous studies, serotonin modulated the cytokine network, and patients with asthma had elevated levels of plasma serotonin.
In addition, they will have the option of interrogating the tumor microenvironment to understand the immune cell content, cytokine network and pro-inflammatory or immune-suppressive pathways in the tumor.
An imbalance of helper T-cells (Th) and variations in the complex and susceptible cytokine network [35, 36] play an important role in the pathogenesis of SLE.
The authors suggest that AIF-1 is closely associated with the pathogenesis of RA and is a novel member of the cytokine network involved in the immunological processes underlying RA.
Complex cytokine network is synthesized as a result of activation of immune system and it plays an important role in periodontal disease.
Winkler, "Age-related changes in intracellular cytokine expression in healthy children," European Cytokine Network, vol.
What is more meaningful is to provide some morphological basis for investigating the role of the cytokine network in pregnancy.
Activation of the CNS cytokine network leads to a cascade of effects such as disturbed metabolism of amino acids, neurotoxicity, diminished neurotrophic support, decreased neurogenesis, impaired negative feedback regulation of HPA axis function and glucocorticoid resistance.
In combination with the variety of the sources of cytokines it is possible to expect the reactive realignment of cytokine network in many (unless all) diseases.