cytokine inhibitors

cytokine inhibitors; anti-TNF alpha agents biological disease-modifying antirheumatic drugs (DMARDs) that inhibit tumour necrosis factor-alpha formation; used to treat autoimmune- mediated inflammatory conditions (ankylosing spondylitis and rheumatoid arthritis); e.g. infliximab; adalimumab, enteracept
References in periodicals archive ?
Yet several trials have shown that patients who do not respond to traditional antidepressants frequently begin to improve when they take anti-inflammatory medications, from everyday ibuprofen to cytokine inhibitors, on top of their other prescriptions.
Fourteen trials informed the meta-analysis, 10 that evaluated NSAID drugs (for example, celecoxib, naproxen, ibuprofen), and 4 that investigated cytokine inhibitors (for example, etanercept, infliximab).
Fourteen trials informed the meta-analysis: 10 that evaluated NSAID drugs (for example, celecoxib, naproxen, ibuprofen), and 4 that investigated cytokine inhibitors (for example, etanercept, infliximab).
As part of the acquisition, Cephalon will gain rights to the BDC intellectual property estate covering the use of cytokine inhibitors, including TNF inhibitors, for sciatic pain in patients with intervertebral disk herniation, as well as other spinal disorders.
Nine chapters are new to this edition, on cytokine inhibitors, potential biologic therapies, pain mechanisms and management, vasculitis classification, Wegener's and anti-neutrophil cytoplasmic antibody-associated vasculitis, polyarteritis nodosa and microscopic polyarterities, hypersensitivity vasculitis, Behcet's syndrome, and other vasculitis syndromes.
The biological and clinical rationale for the use of cytokine inhibitors across major inflammatory diseases is compelling, and oral agents such as pralnacasan have the potential to transform the way that diseases such as RA, OA and psoriasis are treated," stated Vicki Sato, Ph.
The combined use of such cytokine inhibitors, including inhibitors to TNF-alpha, interferon-alpha (IFN-alpha) and interferon-gamma (IFN-gamma) to treat AIDS is protected by the Company's intellectual property.
Elidel (pimecrolimus) are non-steroid, selective cytokine inhibitors that do not cause the skin atrophy, blood vessel growth, glaucoma or growth retardation associated with corticosteroids
The most promising new strategies on the horizon are those that target the joints with higher specificity, such as novel cytokine inhibitors.
Selectide is contributing its proprietary drug discovery technology to the collaboration, while Synergen brings its preclinical and clinical experience with cytokine inhibitors including TNF binding proteins and ANTRIL(TM), the company's IL-1 receptor antagonist (IL-1ra), now in clinical trials for a number of indications including sepsis syndrome.