KRT20

(redirected from cytokeratin-20)

KRT20

A gene on chromosome 17q21.2 that encodes a type-I keratin, an intermediate filament protein that is a major cellular protein of mature enterocytes and goblet cells, and is specifically expressed in gastric and intestinal mucosa.
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Follicular stem cell marker PHLDA1 (TDAG51) is superior to cytokeratin-20 in differentiating between trichoepithelioma and basal cell carcinoma in small biopsy specimens.
These studies have used the polymerase chain reaction (PCR) detection method of cytokeratin-20 (CK-20)-positive cells to detect CTCs.