KRT1

(redirected from cytokeratin-1)

KRT1

A gene on chromosome  12q13.13 that encodes a type-II cytokeratin that is specifically co-expressed in the spinous and granular layers of the epidermis with KRT10.
 
Molecular pathology
KRT1 mutations are associated with bullous congenital ichthyosiform erythroderma, ichthyosis hystrix and Curth-Macklin type.