KRT10

(redirected from cytokeratin 10)

KRT10

A gene on chromosome 17q21 that encodes a type-I (acidic) member of the cytokeratin family, which belongs to the superfamily of intermediate filaments, that with actin microfilaments and microtubules forms the epithelial cell cytoskeleton.

Molecular pathology
KRT10 mutations cause epidermolytic hyperkeratosis.
References in periodicals archive ?
Sections were assessed for surfactant protein A (sc-7699), Clara cell protein 10 (sc-9772), cytokeratin 10 (sc-58720), and cytokeratin 14 (sc-53253) using antibodies from Santa Cruz Biotechnology (Santa Cruz, CA, USA) and cytokeratin 19 (CRC946) from Cell Marque (Rocklin, CA, USA).
These lesions were negative lor the squamous epithelial markers cytokeratin 10 and 14, as indicated by a lack pi brown staining (Figure 2B,C).