KRT10

(redirected from cytokeratin 10)

KRT10

A gene on chromosome 17q21 that encodes a type-I (acidic) member of the cytokeratin family, which belongs to the superfamily of intermediate filaments, that with actin microfilaments and microtubules forms the epithelial cell cytoskeleton.

Molecular pathology
KRT10 mutations cause epidermolytic hyperkeratosis.
References in periodicals archive ?
For immunohistofluorescence staining, cross sections were hydrated and subjected to antigen retrieval in tris-ethylenediaminetetraacetic acid buffer (cytokeratin 14, cytokeratin 10, filaggrin, collagen type IV, CD-31, von Willebrand Factor) or citrate buffer (vimentin) for 20 minutes at 100[degrees]C.
However decompression reduces cystic volume and allows removal of 1L-1@ and cytokeratin 10 which is related to expansion of cyst.
These authors also demonstrated that the altered expression of cytokeratin 10 is a marker of epithelial changes that occur in large KOTs submitted to marsupialization.