cytogenetics

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Related to cytogenetically: cytogeneticists, Cytogenetic analysis

cytogenetics

 [si″to-jĕ-net´iks]
that branch of genetics devoted to the cellular constituents concerned in heredity, i.e., the chromosomes.
clinical cytogenetics the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathologic conditions.

cy·to·ge·net·ics

(sī'tō-jĕ-net'iks),
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes.

Cytogenetics arose as a fusion of 19th-century cytology and 20th-century genetics, which came into being in 1903 with the articulation of the chromosome theory of inheritance. The developing field concerned itself with detailing the behavior of chromosomes and their functional subunits, the genes, during reproduction, and with relating that behavior statistically to characteristics of the resulting cells or animals. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been fixed in mitosis and stained with various agents to delineate characteristic bands. DNA probes can be applied to locate specific gene sequences. Karyotyping is the arrangement of photographs of stained chromosomes in a standard format. Cytogenetic techniques are used to test for inborn errors of metabolism and genomic aberrations such as Down syndrome and to determine sex in cases where anatomy is inconclusive.

cytogenetics

/cy·to·ge·net·ics/ (-jĕ-net´iks) the branch of genetics devoted to cellular constituents concerned in heredity, i.e. chromosomes.
clinical cytogenetics  the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathologic conditions.

cytogenetics

(sī′tō-jə-nĕt′ĭks)
n. (used with a sing. verb)
The branch of genetics that deals with the cellular components, particularly chromosomes, that are associated with heredity.

cy′to·ge·net′ic, cy′to·ge·net′i·cal adj.
cy′to·ge·net′i·cal·ly adv.
cy′to·ge·net′i·cist (-sĭst) n.

cytogenetics

[sī′tōjənet′iks]
the branch of genetics that studies the cellular constituents concerned with heredity, primarily the structure, function, and origin of the chromosomes. One kind of cytogenetics is clinical cytogenetics. Also called cytogenics.

cy·to·ge·net·ics

(sī'tō-jĕ-net'iks)
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been arranged as karyotypes. Individuals can be classified according to characteristic banding patterns that appear when the karyotypes are exposed to some dyes. In addition, DNA probes may be applied to locate specific gene sequences. Cytogenetic techniques are used to test for inborn errors of metabolism, for disorders such as Down syndrome, and to determine sex in cases where anatomy is inconclusive.

cytogenetics

the study of the inheritance of cells and their chromosomes. Cytogenetic analysis of foetal cells (see AMNIOCENTESIS and CYSTIC FIBROSIS) is used to assess potential risks to the baby.

cytogenetics

that branch of genetics devoted to the cellular constituents concerned in heredity, i.e. the chromosomes; the combined sciences of genetics and cytology.

clinical cytogenetics
the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathological conditions.
References in periodicals archive ?
The genus Brachistosternus was studied cytogenetically for the first time by Giacomozzi (1977) (Tab.
Thus, with the increase of the number of cytogenetically analyzed species, a better understanding of the characteristics of the genus can be obtained to help in understanding the processes that led to changes in karyotype of the group and the relationships among species.
4,5) Results of bone marrow studies 3 weeks later were morphologically, immunophenotypically, and cytogenetically consistent with B-cell lineage ALL.
Cytogenetically, MS occurs in association with a variety of chromosomal abnormalities, including MLL gene rearrangement and t(8,21) (6); the latter more often occurs in childhood and/or is seen in lesions occurring in the orbit (7).
Cytogenetically, clear cell papillary RCC lacks typical abnormalities seen in either clear cell RCC or papillary RCC.
Cytogenetically mosaic tumors were also reported to be clonal (6).
The Weghofer I study showed a greater number of cytogenetically normal embryos when hMG was used compared with the rFSH group (59.
Until now, only 15 pholcid species have been analyzed cytogenetically, and their diploid number varies from 2n[male] = 15 to 2n[male] = 32.
In the early 1990s, it was found cytogenetically that one and the same chromosome aberration, 22q11 deletion, caused all the above three syndromes (16,17).
In fact, available karyologic data on the class Gastropoda indicate that more than 300 species have been analyzed cytogenetically, whereas <20 of them have been examined using this kind of techniques (Vitturi et al.
Because at least one-half of fibroid tumors appear to be cytogenetically normal, there may exist an unidentified submicroscopic mutation in this karyotypically normal subgroup or even in the cytogenetically abnormal group as well.