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cytochrome P-450

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cytochrome P-450
Etymology: Gk, kytos, cell, chroma, color
a protein involved with extramitochondrial electron transport in the liver and during drug detoxification.
cytochrome P-450
Clinical pharmacology A superfamily of heme-containing enzymes–CYPs of the electron transport chain, which have multiple activities, including activation of molecular O2 for incorporation into unactivated hydrocarbons, xenobiotic metabolism, bioremediation, and breakdown of drugs and toxins
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In January 2008, researchers at Duke University Medical Center (Durham, North Carolina) reported that Splenda negatively affected gastrointestinal flora and the cytochrome P-450 detoxification system in male rats.
Splenda affects gut by Klotter, Jule / Townsend Letter
ibuprofen for cyclooxygenase, SKF-525A for cytochrome P-450, baicalein and BHPP for 12-lipoxygenase, AA861 and MK886 for 5-lipoxygenase, etc.
Arachidonic acid stimulates prostate cancer cell growth: critical ... by Life Extension
The microsomal pellets obtained were carefully collected and used for the estimation of cytochrome P-450 and b5 (Omura and Sato, 1964).
Enzymatic Studies of Etoposide- Induced Oxidative Stress in Hepatic ... by Pratibha R.Kamble / Biological sciences community
 
 
 
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