CTNS

(redirected from cystinosin, lysosomal cystine transporter)

CTNS

A gene on chromosome 17p13 that encodes a 7-transmembrane domain protein, which transports cystine out of lysosomes driven by the H+ electrochemical gradient of the lysosomal membrane.

Molecular pathology
CTNS mutations cause nephropathic cystinosis, a lysosomal storage disease.