cystathionine


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cystathionine

 [sis″tah-thi´o-nēn]
a thioester of homocysteine and serine; it serves as an intermediate in the transfer of a sulfur atom from methionine to cysteine.

cys·ta·thi·o·nine

(sis'tă-thī'ō-nēn),
The l-isomer is an intermediate in the conversion of l-methionine to l-cysteine; cleaved by cystathionases.

cystathionine

/cys·ta·thi·o·nine/ (-nēn) a thioester of homocysteine and serine; it serves as an intermediate in the transfer of a sulfur atom from methionine to cysteine.

cys·ta·thi·o·nine

(sis'tă-thī'ō-nēn)
An intermediate in the conversion of l-methionine to l-cysteine; cleaved by cystathionases.

cystathionine

key intermediate in the trans-sulfuration pathway from methionine to cysteine.
References in periodicals archive ?
Cystathionine was generated by transmethylation in the process of Met metabolism [23], and then cystathionine transsulfuration produced cysteine [24], and cysteine finally transformed into taurine [25], which plays important roles in antioxidant [24].
His homocysteine improved but his mismatch with cystathionine worsened so we added in the activated form of vitamin B6 in the pyridoxyl 5-phosphate (P-5-P) form.
If methionine is in excess than homocysteine is irreversibly converted to cysteine by cystathionine beta synthase with vitamin B6 as cofactor.
In addition to the above-mentioned S-sulfhydrated proteins, S-sulfhydration of cystathionine [beta]-synthase (CBS) and cystathionine [gamma]-lyase (CSE), [H.
Cystathionine beta-synthase or thermolabile methylenetetrahydrofolate reductase enzymes, and vitamins like B12, B6 and folic acid are the cofactors in the metabolism of Hcy.
Key enzymes involved in the one-carbon methylation of As with S-adenosyl methionine (SAM) as the methyl donor include arsenic-3-methyltransferase (AS3MT), methylenetetrahydrofolate reductase (MTHFR), cystathionine beta-synthase (CBS), and PNP.
2]S facilitates the induction of hippocampal long-term potentiation (LTP) by enhancing the activity of N-methyl D-aspartate (NMDA) receptors, and that cystathionine [beta]-synthase (CBS) produces [H.
The natural history of homocystinuria due to cystathionine beta-synthase deficiency.
Well-rounded support for methylation (MET) as well as cystathionine beta synthase (CBS) pathways appeared well tolerated in this study.
Third, the transsulfuration pathway from homocysteine to cystathionine which is catalyzed by cystathionine beta synthase (CBS) is tightly related to the methylation pathway.
Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma-cystathionase?
Cystathionine- This enzyme acts in a chemical pathway and is P-synthase responsible for using vitamin B6 to convert building block of proteins (amino acid) called homocysteine and serine to a molecule called cystathionine.