cyclosporine

cyclosporine /cy·clo·spor·ine/ (-spor´en) a cyclic peptide from an extract of soil fungi that selectively inhibits T cell function; used as an immunosuppressant to prevent rejection in organ transplant recipients and to treat severe psoriasis and severe rheumatoid arhtritis.

---

cy·clo·spor·ine (skl-spôrn, -n) or cy·clo·spor·in A (-n)

n.

A cyclic oligopeptide immunosuppressant produced by fungus and used to inhibit organ transplant rejection.

---

cyclosporine (sī´klōspor´ēn),

n brand name: Sandimmune;
drug class: immunosuppressant;
action: produces immunosuppression by inhibiting lymphocytes;
uses: to prevent rejection of tissues and/or organ transplants.

---

cyclosporine

a neutral cyclic peptide, the major metabolic product of the fungus Tolypocladium inflatum; a specific suppressor of the T lymphocyte response, important in tissue transplantation.