cycloserine


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Related to cycloserine: Ethionamide

cycloserine

 [si″klo-ser´ēn]
an antibiotic elaborated by Streptomyces orchidaceus or produced synthetically, used as a tuberculostatic and in the treatment of urinary tract infections.

cy·clo·ser·ine

(sī'klō-ser'ēn),
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.
Synonym(s): orientomycin

cycloserine

/cy·clo·ser·ine/ (-sĕ´rēn) an antibiotic produced by Streptomyces orchidaceus or obtained synthetically; used as a tuberculostatic and in treatment of urinary tract infections.

cycloserine

(sī′klō-sĕr′ēn)
n.
An antibiotic effective against a wide range of bacteria, used especially in the treatment of tuberculosis and infections of the urinary tract.

cycloSERINE

[sī′klōser′ēn]
an antibiotic.
indications It is prescribed in the treatment of active pulmonary and extrapulmonary tuberculosis.
contraindications Epilepsy, depression, severe anxiety, psychosis, severe renal insufficiency, excessive concurrent use of alcohol, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious reactions are central nervous system toxic effects, including tremor, drowsiness, convulsions, and psychotic changes. Pyridoxine may be given concurrently to prevent these effects. Other side effects include arrhythmias and optic neuritis.

cycloserine

Infectious disease A broad-spectrum antibiotic used for UTIs and TB Adverse effects CNS Sx, allergy, skin rash, ↑ LFTs

cy·clo·ser·ine

(sī'klō-ser'ēn)
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.

cycloserine

A drug used to treat TUBERCULOSIS caused by organisms resistant to treatment by standard drugs such as rifampicin, isoniazid, ethambutol and streptomycin. The drug is on the WHO official list.

cy·clo·ser·ine

(sī'klō-ser'ēn)
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.

cycloserine (sī´klōserēn),

n brand name: Seromycin Pulvules;
drug class: antitubercular;
action: inhibits cell wall synthesis, analog of D-alanine;
uses: pulmonary tuberculosis.
References in periodicals archive ?
We removed the test from the CPOE order menu, thereby eliminating the possibility that a cycloserine level test would be ordered in error when a clinician desired a cyclosporine level, leading to a delay in obtaining the necessary result.
Because several physicians directly contacted our laboratory to inquire about the reason behind the trace or low test results for cycloSPORINE, our conclusion was that referring laboratory A likely entered a wrong test request for cycloSERINE instead of cycloSPORINE.
The ability to manufacture cycloserine locally is essential to treating the plight of multidrug resistance in South Africa," said Mr.
After close consultation with global TB experts, Lilly embarked on a novel approach: transferring its manufacturing technology and know-how for capreomycin and cycloserine to seven manufacturers.
difficile isolates, 100 per cent were inhibited by low concentrations of metronidazole, penicillin G, tetracycline and ampicillin, but were highly resistant to gentamycin, trimethoprim, sulphamethoxazole, nalidixic acid, cycloserine and cefotaxime.
It is a large microbe and grows well on a culture medium consisting of cycloserine, cefoxitin, and fructose agar in an egg-yolk agar base.
Another centerpiece of Lilly's MDR-TB Partnership is the transfer of technologies and expertise needed to manufacture two Lilly antibiotics used to treat MDR-TB, capreomycin (Capastat(R)) and cycloserine (Seromycin(R)), to facilities in the highest-burdened countries.
Second-line drugs--with little or no scientific evidence to support their use--include cycloserine, ethionamide, streptomycin, amikacin/kanamycin, capreomycin, paminosalicylic acid, levofloxacin, moxifloxacin, and gatifloxacin.
1,4) Mycobacterium kansasii is usually susceptible to streptomycin, rifampin, ethambutol, erythromycin, cycloserine, aminosalicylic acid, and isoniazid.
In response, the South African Department of Health prepared a draft drug-resistant TB treatment policy in which PZA remains one of the 4 effective drugs, while EMB should be replaced with terizidone or cycloserine, if there is resistance to EMB (disregarding inaccurate DST).
1% Tween 80 (MP Biochemicals, Solon, OH, USA), cycloserine (1 mg/mL; Sigma-Aldrich, St Louis, MO, USA), and ampicillin (0.
difficile was done on cycloserine cefoxitin fructose agar (CCFA) and brain heart infusion agar (BHIA) as described elsewhere (6).