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cyclopia

   Also found in: Dictionary/thesaurus, Legal, Financial, Encyclopedia, Wikipedia 0.01 sec.
cyclopia /cy·clo·pia/ (si-klo´pe-ah) a developmental anomaly marked by a single orbital fossa, with the globe absent, rudimentary, apparently normal, or duplicated, or the nose absent or present as a tubular appendix above the orbit.
cy·clo·pi·a (s-klp-)
n.
A congenital defect in which the two orbits merge to form a single cavity containing one eye. Also called synophthalmia.

cyclopia
[sīklō′pē·ə]
Etymology: Gk, Cyclops, mythic one-eyed giant
a developmental anomaly characterized by fusion of the orbits into a single cavity containing one eye. The condition is usually combined with various other head and facial defects. Also called cyclocephaly, synophthalmia. cyclops, n.

Cyclopia
The presence of a single, large centrally located eye—which may be a non-functional, if present, proboscis—and a single upper front incisor. It is caused by a failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities, possibly related to a defect in cholesterol transport

anomaly [ah-nom´ah-le]
marked deviation from normal. adj., adj anom´alous.
Axenfeld's anomaly a developmental anomaly characterized by a circular opacity of the posterior peripheral cornea, and caused by an irregularly thickened, axially displaced Schwalbe's ring.
congenital anomaly (developmental anomaly) absence, deformity, or excess of body parts as the result of faulty development of the embryo.
Ebstein's anomaly see ebstein's anomaly.
May-Hegglin anomaly a rare dominantly inherited disorder of blood cell morphology, characterized by RNA-containing cytoplasmic inclusions (similar to Döhle bodies) in granulocytes, by large, poorly granulated platelets, and by thrombocytopenia.

cyclopia
a developmental anomaly characterized by a single orbital fossa, with the globe absent or rudimentary, apparently normal, or duplicated, or the nose absent or present as a tubular appendix located above the orbit and absence of the maxillae. Important animal occurrences of cyclopia are in one of the forms of inherited prolonged gestation, and in poisoning by veratrumcalifornicum.

cyclopia
Neonatology The presence of a single, large centrally located eye, which may be accompanied by a single upper front incisor, and is due to a developmental defect related to cholesterol transport. See Fraser syndrome.


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