cyclopia


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anomaly

 [ah-nom´ah-le]
marked deviation from normal. adj., adj anom´alous.
Axenfeld's anomaly a developmental anomaly characterized by a circular opacity of the posterior peripheral cornea, and caused by an irregularly thickened, axially displaced Schwalbe's ring.
congenital anomaly (developmental anomaly) absence, deformity, or excess of body parts as the result of faulty development of the embryo.
Ebstein's anomaly see ebstein's anomaly.
May-Hegglin anomaly a rare dominantly inherited disorder of blood cell morphology, characterized by RNA-containing cytoplasmic inclusions (similar to Döhle bodies) in granulocytes, by large, poorly granulated platelets, and by thrombocytopenia.

cy·clo·pi·a

(sī-klō'pē-ă),
A congenital defect in which the two orbits are united to form a single cavity containing one eye, which typically results from union of the right and left optic primordia, usually combined with holoprosencephaly or cyclencephaly.
[G. Kyklōps, fr. kyklos, circle, + ōps, eye]

cyclopia

/cy·clo·pia/ (si-klo´pe-ah) a developmental anomaly marked by a single orbital fossa, with the globe absent, rudimentary, apparently normal, or duplicated, or the nose absent or present as a tubular appendix above the orbit.

cyclopia

[sīklō′pē·ə]
Etymology: Gk, Cyclops, mythic one-eyed giant
a developmental anomaly characterized by fusion of the orbits into a single cavity containing one eye. The condition is usually combined with various other head and facial defects. Also called cyclocephaly, synophthalmia. cyclops, n.
enlarge picture
Cyclopia in a neonate
The presence of a single, large centrally located eye—which may be a non-functional, if present, proboscis—and a single upper front incisor. It is caused by a failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities, possibly related to a defect in cholesterol transport

cyclopia

Neonatology The presence of a single, large centrally located eye, which may be accompanied by a single upper front incisor, and is due to a developmental defect related to cholesterol transport. See Fraser syndrome.

cy·clo·pi·a

(sī-klō'pē-ă)
A congenital defect in which the two orbits are united to form a single cavity containing one eye, its origin evidenced by fusion of the right and left optic primordia, and in which the nose is absent; usually combined with cyclencephaly.
Synonym(s): synophthalmia.
[G. Kyklōps, fr. kyklos, circle, + ōps, eye]

cyclopia

A congenital deformity featuring fusion of the eye sockets and the eyes, so that there appears to be only a single median eye.

cyclopia

the possession of a single median eye.

cyclopia

a developmental anomaly characterized by a single orbital fossa, with the globe absent or rudimentary, apparently normal, or duplicated, or the nose absent or present as a tubular appendix located above the orbit and absence of the maxillae. Important animal occurrences of cyclopia are in one of the forms of inherited prolonged gestation, and in poisoning by veratrumcalifornicum.
References in periodicals archive ?
We have previously reported that hot water extracts of two endemic South African plants, Cyclopia maculata and Cyclopia sub-ternata inhibit adipocyte differentiaton in 3T3-L1 adipocytes, thus suggesting their anti-obesity potential (Dudhia et al.
Cyclopia maculata and Cyclopia subternata (honeybush tea) inhibits adipogenesis in 3T3-L1 pre-adipocytes.
South African herbal teas: Aspalathus 1 inearis, Cyclopia spp.
The genus Cyclopia is indigenous to the southeast and southwest coastal areas of South Africa.
The presence or absence of compounds previously identified in Cyclopia spp.
The effects of fermentation (the oxidation of phenolic compounds required for the development of the characteristic sweet aroma and flavour of honeybush tea) on lowering polyphenolic content, especially mangiferin, and decreasing anti-oxidant activity has been previously reported for Aspalathus linearis and other Cyclopia spp.
This is the first study to illustrate that Cyclopia has anti-obesity properties.
Development of HPLC method for Cyclopia subternata phenolic compound analysis and application to other Cyclopia spp.
Phenolic compounds from Cyclopia Intermedia (honeybush tea).
Isolation and structure elucidation of phenolic compounds from Cyclopia subtemata Vogel (honeybush) intact plant and in vitro cultures.