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cyclophosphamide

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cyclophosphamide /cy·clo·phos·pha·mide/ (-fos´fah-mid) a cytotoxic alkylating agent of the nitrogen mustard group; used as an antineoplastic, as an immunosuppressant to prevent transplant rejection, and to treat some diseases characterized by abnormal immune function.
cy·clo·phos·pha·mide (skl-fsf-md)
n.
A highly toxic, immunosuppressive, antineoplastic drug, used in the treatment of Hodgkin's disease, lymphoma, and certain other forms of cancer, such as leukemia and breast cancer.

cyclophosphamide (sīklōfos´fmīd´),
n brand names: Cytoxan, Neosar, Procytox;
drug class: antineoplastic alkylating agent;
action: alkylates DNA, RNA; inhibits enzymes that allow synthesis of amino acids in proteins;
uses: Hodgkin's disease; lymphomas; leukemia; cancer of female reproductive tract, lung, prostate; multiple myeloma; neuroblastoma; retinoblastoma; Ewing's sarcoma.

cyclophosphamide
a neoplastic suppressant used in the treatment of lymphomas and leukemias.

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The treatment of choice is chemotherapy, which usually includes cyclophosphamide, vincristine, and prednisone.
ovatus) were pooled and intraperitoneally injected into 15 ddY male mice (6-15 pooled ticks per mouse) treated with the immunosuppressant cyclophosphamide.
Pharmacokinetic studies suggested a significant decrease in cyclophosphamide clearance, but no obvious affects on the other drugs.
 
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