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Cyclooxygenase

   Also found in: Dictionary/thesaurus, Acronyms, Wikipedia 0.06 sec.
cyclooxygenase /cy·clo·oxy·gen·ase/ (-ok´si-jen-as) a component of prostaglandin synthase (q.v.).
Cyclooxygenase
An enzyme, found in most tissues, that helps turn some fatty acids into protaglandins.
Mentioned in: Cox-2 Inhibitors
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For example, opioids, such as morphine, promote analgesia not through an anti-inflammatory action like that of an NSAID that inhibits the cyclooxygenase enzyme but by directly counteracting the sensitization of the primary afferent nociceptors or by blocking nociceptive transmission in the spinal cord.
Interferential therapy produces antinociception during application in ... by Tambeli, Claudia H. / Physical Therapy
The team then tested whether oleocanthal could chemically inhibit two inflammation-inducing enzymes, cyclooxygenase (COX) 1 and COX 2.
Olives alive: extra-virgin oil has anti-inflammatory properties by Brownlee, C. / Science News
ibuprofen found in Advil[R] and Motrin[R], are cyclooxygenase (COX)-1 and COX-2 inhibitors.
NSAIDs have their limits in treating OA pain by Running & FitNews
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