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cyclooxygenase |
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cyclooxygenase /cy·clo·oxy·gen·ase/ (-ok´sĭ-jen-ās) a component of prostaglandin synthase (q.v.). Cyclooxygenase An enzyme, found in most tissues, that helps turn some fatty acids into protaglandins. Mentioned in: Cox-2 Inhibitors cyclooxygenase [si′klō·ok′səjĕnās] an activity of the enzyme prostaglandin endoperoxide synthase. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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For example, opioids, such as morphine, promote analgesia not through an anti-inflammatory action like that of an NSAID that inhibits the cyclooxygenase enzyme but by directly counteracting the sensitization of the primary afferent nociceptors or by blocking nociceptive transmission in the spinal cord. The team then tested whether oleocanthal could chemically inhibit two inflammation-inducing enzymes, cyclooxygenase (COX) 1 and COX 2. ibuprofen found in Advil[R] and Motrin[R], are cyclooxygenase (COX)-1 and COX-2 inhibitors. |
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