cyclo-oxygenase-2 inhibitor


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cyclo-oxygenase-2 inhibitor (COX-2)

One of a range of drugs similar in action to NON-STEROIDAL ANTI-INFLAMMATORY drugs. A COX-2 inhibitor drug refoecoxib (Vioxx) was withdrawn in September 2004 when it was found to increase the risk of heart attacks and stroke.
References in periodicals archive ?
Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis.
Dajani EZ, Islam K 2008 Cardiovascular and gastrointestinal toxicity of selective cyclo-oxygenase-2 inhibitors in man Journal of Physiology & Pharmacology 59 117-133
Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-in-flammatory drugs: population based nested case control analysis.
Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis.