cyclo-oxygenase-2 inhibitor


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cyclo-oxygenase-2 inhibitor (COX-2)

One of a range of drugs similar in action to NON-STEROIDAL ANTI-INFLAMMATORY drugs. A COX-2 inhibitor drug refoecoxib (Vioxx) was withdrawn in September 2004 when it was found to increase the risk of heart attacks and stroke.
References in periodicals archive ?
Bad publicity about increased risk for heart attacks and strokes with cyclo-oxygenase-2 inhibitors gave his patients pause.
LOS ANGELES -- The sharp decline in the use of selective cyclo-oxygenase-2 inhibitors due to concerns about cardiovascular risks has created a "gastroprotection gap" among elderly arthritis patients who require NSAIDs, Dr.