We will design tubular supramolecular polymers, supramolecular polymer brushes (SPBs), based on the self-assembly of cyclic peptide
Facile synthesis of orthogonally protected amino acid building blocks for combinatorial N-backbone cyclic peptide
Some rrs mutations also confer resistance to the cyclic peptide
antibiotic CAP .
In our study, the cyclic peptide
, Pep42, CTVALPGGYVRVC, was selected for its ability to target and internalize within the Glucose Regulated Protein 78 (GRP78) harboring tumor cell lines.
Chemicals called cyclic peptide
inhibitors can stop sweet-toothed cancer cells from growing.
mMass as a software tool for the annotation of cyclic peptide
tandem mass spectra.
Isolation, structural characterization, and properties of mattacin (polymyxin M), a cyclic peptide
antibiotic produced by Paenibacillus kobensisM.
Microcystin-LR, a cyclic peptide
released by several bloom-forming toxic cyanobacteria, is a potent cytotoxicant and has been shown to induce cellular proliferation resulting in a tumor-promoting activity in hepatocytes.
The yield of this 5-KDa water soluble cyclic peptide
Seventeen CYA metabolites are known, all retain the cyclic peptide
structure, with mono- and di-hydroxylation and/or N-demethylation biotransformations occurring.
Topics of the 15 chapters include modification of peptides and other drugs using lipoamino acids and sugars, synthesis of cell-penetrating peptides for cargo delivery, expressed protein ligation for protein semi-synthesis and engineering, quenched fluorescent substrate-based peptidase assays, cyclic peptide
libraries, and peptide bioconjugates.
The group, however, has had difficulty closing the nine-unit cyclic peptide
, which is a shortchain protein.