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cyclic neutropenia

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cyclic neutropenia

cyclic neutropenia
[sik′lik no̅o̅′trōpē′nē·ə]
a chronic type of neutropenia that abates and recurs, accompanied by malaise, fever, stomatitis, and various types of infections.

cyclic neutropenia (nōō´trpē´nē),
n a hereditary disease primarily afflicting young children and infants; characterized by flulike symptoms (weakness, tenderness in the pharynx, aching head, and fever) as well as stomatitis, periodontitis, and gingivitis; cycles every 3 to 4 weeks with painful lesions and damage to the alveolar bone; should be medicated with antibiotics prior to any oral surgery.

cyclic
pertaining to or occurring in a cycle or cycles. The term is applied to chemical compounds that contain a ring of atoms in the nucleus.

cyclic adenosine monophosphate (AMP)
see cyclic adenosine monophosphate.
cyclic guanosine monophosphate (cGMP)
see cyclic guanosine monophosphate.
canine cyclic hematopoiesis
an abnormality of hematopoietic stem cells that results in detectable, cyclic fluctuations in numbers of circulating neutrophils. Affected dogs have an increased susceptibility to infections. The condition is inherited as an autosomal recessive in collies where it is occurs with a distinctive silver-gray coat color; called also gray collie syndrome.
cyclic neutropenia
see canine cyclic hematopoiesis (above).
cyclic non-breeder cows
cows demonstrating estrus regularly but not being submitted for mating; deferral of mating.
cyclic nucleotide
see cyclic nucleotide.

neutropenia
a diminished number of neutrophils in the blood.

cyclic neutropenia
periodic neutropenia. See also canine cyclic hematopoiesis.
malignant neutropenia
agranulocytosis.
periodic neutropenia
see canine cyclic hematopoiesis.

cyclic neutropenia
A disorder characterized by episodic severe neutropenia occurring in 3-4 wk cycles, accompanied by maturational arrest of myeloid precursors in BM Clinical Fever, oral ulceration, cervical lymphadenopathy, multiple acute local infections which are rarely fatal Management If symptomatic, antibiotics–eg, aminoglycosides, penicillin


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