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cyclic guanosine monophosphate |
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guanosine /gua·no·sine/ (gwah´no-sēn) a purine nucleoside, guanine linked to ribose; it is a component of RNA and its nucleotides are important in metabolism. Symbol G. cyclic guanosine monophosphate 3′,5′-GMP, cGMP, cyclic GMP; a cyclic nucleotide that acts as a second messenger similar in action to cyclic adenosine monophosphate but generally producing opposite effects on cell function. guanosine monophosphate (GMP) a nucleotide important in metabolism and RNA synthesis. guanosine triphosphate (GTP) an energy-rich compound involved in several metabolic reactions and an activated precursor in the synthesis of RNA.
cyclic guanosine monophosphate (cGMP), a substance that mediates the action of certain hormones in a manner similar to that of cyclic adenosine monophosphate. In response to the stimulation of cholinergic receptors in a parasympathetic nerve, guanylate cyclase triggers the conversion of guanosine triphosphate to cGMP with the release of various enzymes. Atropine, an anticholinergic drug, can block cholinergic stimulation by means of this process. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Known as cyclic guanosine monophosphate, or cGMP, the chemical may also play a role in the normal control of any mammal's digestive system. 5) CGRP acts on endothelial receptors and activates a series of intracellular processes that ultimately lead to an increase in cyclic guanosine monophosphate levels and resultant vasorelaxation. Nitric oxide is a biogenic messenger, an EDRF (15,16), and it activates the guanylyl cyclase system (17) [it converts guanosine triphosphate to cyclic guanosine monophosphate (cGMP)], raising the cGMP pool and therefore inducing, among other things, vasodilatation (17) by lowering the intracellular calcium ion (16). |
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