cyclamates


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Related to cyclamates: aspartame, saccharin

cyclamates

A family (calcium cyclamate and its metabolites, cyclohexylamine, cyclamic acid and sodium cyclamate) of artificial sweeteners, banned by the FDA in 1970 when they were linked to bladder cancer in rats given extremely high doses. Subsequent studies have failed to reveal direct, intrinsic genotoxicity of cyclamate, although when added to saccharin (another artificial sweetener), there was an additive tumourigenic effect, causing a focal increase in tumours of the bladder epithelium.
References in periodicals archive ?
Spokesman Dr Tim Lobstein said: "Their sperm count might be reduced because tests have shown that excessive levels of cyclamates could reduce testosterone levels and shrivel the size of the testicles.
Some food dyes, cyclamates and other artificial sweeteners all eventually had to be pulled from the market, but it took decades from the time the FDA approval was awarded.
In general, the new legislation provides for the continued use of those additives currently permitted but also permits the use of some additional additives; these include cyclamates for use as sweeteners in certain foods.
I know I used a lot of saccharine and cyclamates in my life.
had barred the use of cyclamates reached Japan, all major soft drink producers took put large ads in newspapers and on television reassuring Japanese consumers that they had not been using cyclamates and strongly apologized for causing them concern.
Food and Drug Administration, the committee spent more than a year reviewing all existing studies on cyclamates and cancer.
1969 - Cyclamates, used to sweeten soft drinks, are labeled cancer-causers and taken off the market.
Indeed, scientists are questioning regulations governing such chemicals as dioxin, DDT, saccharin and cyclamates, which have produced cancers in some lab animal test but may not be as harmful to humans.
The category of HIS includes saccharin, acesulfame-K, aspartame, neotame, cyclamates, sucralose and alitame.