This has been suggested after the discovery of cycasin
from Cycas in 1979 (Matsushima et al.
As early as the 1960s, researchers knew that the bacterial enzyme beta-glucoronidase converts a plant chemical called cycasin
into a carcinogen.
Because he's failed to produce the full, progressive disease in monkeys by dosing them with BMAA, he's now pursuing cycasin
, another cycad compound.
You cycad fans can relax: properly washing cycad nuts removes the "possibly" carcinogenic cycasin
Compounds being tested include methylmethoxymethanol, which comes from the naturally occurring toxin cycasin
(from a plant in the cycad family), as well as N-methyl-N-nitrosourea and methyl methane sulfonate, both of which are synthetic compounds found in grilled foods and smoke.
and BMAA in cycad flour prepared by Guam Chamorros.
, methylazoxymethanol and related compounds.
neurotoxins such as cycasins
, macrozamins, and BMAA (Whiting, 1963;