cyanogen bromide


Also found in: Acronyms, Encyclopedia, Wikipedia.

cyanogen bromide

reagent used to fragment peptide chains, since it cleaves only those peptide bonds in which methionine contributes the carbonyl group. Also used as coupling agent in affinity chromatography where it reacts with the Sepharose matrix forming a reactive product to which proteins, nucleic acids or other biopolymers can be coupled.
References in periodicals archive ?
For this purpose, a safe method of cyanogen bromide preparation was introduced [54].
Preparing method of cyanogen bromide for activation of agarose.
The main activated agarose matrices used Activation Linkage Available Specificity to agarose reactive group of group Cyanogen bromide Isourea Cyanate ester Amine (finally) Carbonyl- Carbamate Imidazolyl Amine diimidazole carbamate Epichloro-hydrin Ether Epoxy SH > [NH.