culture-negative endocarditis


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culture-negative endocarditis

Cardiology Endocarditis in which a causative microorganism are not identified

culture-negative endocarditis

Infective endocarditis produced by organisms that do not quickly or readily grow in blood cultures, usually because their growth is masked by the previous use of antibiotics or because the causative organisms require special culture media or grow slowly in the laboratory. Mycoplasma, Ricksettsia, HACEK (an acronym for Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, Kingella) organisms, and some fungi produce culture-negative endocarditis.
See: infective endocarditis
See also: endocarditis
References in periodicals archive ?
burnetii in community-acquired, culture-negative endocarditis may be clinically useful, particularly in screening for B.
The modified Duke diagnostic criteria are heavily based upon positive blood cultures, and a low microbiologic yield from blood culture raises questions as to the validity of these criteria in diagnosing culture-negative endocarditis in developing countries.
Second, only 20 patients (13%) underwent transesophageal echocardiography; the prevalence of culture-negative endocarditis may have increased if TEE had been performed on all patients.
Culture-negative endocarditis continues to have a high prevalence in developing countries like Pakistan, largely due to prior antibiotic use before clinical presentation.
Because 16S rRNA PCR is used in many areas to test for blood culture-negative endocarditis, which would enable detection of T.
In the future, blood specimens from patients with blood culture-negative endocarditis should be also inoculated systematically on specific media.
The difference in comparison to other countries is that blood culture-negative endocarditis is mainly linked to zoonotic and arthropodborne agents.
Of the 62 blood culture-negative endocarditis cases, samples from all were tested by serologic or molecular methods.
According to the earliest published report on the subject, the prevalence of blood culture-negative endocarditis once ranged from 2.
Of 66 sera taken from cases of culture-negative endocarditis and sent to the Public Health Laboratory Service in London, United Kingdom, 18% were positive for Bartonella antibodies (8).

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