cryptdin

cryptdin

(krĭp′dĭn)
A cation released from intestinal crypts, as a defense against infection with enteric bacteria. It is part of the innate immune response. Cryptdins destroy bacteria by punching holes in their cell membranes.
References in periodicals archive ?
21 The combination of cryptdin 2 and ampicillin was also found as extremely effective, which indicated in vitro synergy between the two agents.
For instance, NOD2-dependent responses to bacterial peptidoglycan fragments can promote Paneth cells to express antimicrobial cryptdin peptides.
Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium.
Cryptdin 3 forms anion selective channels in cytoplasmic membranes of human embryonic kidney cells.
The granules contain a number of proteins associated with roles in host defense including lysozymes, secretory phospholipase A2, and alpha-defensins termed cryptdins.
In other studies, Cryptosporidium parvum infection activated both CD4+ and CD8+ gamma/delta T cells, and Giardia species stimulated the release of several effector molecules, including defensins, cryptdins, and indolicidin.