crossmatching of blood

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Etymology: L, crux + AS, gemaecca, matching

a procedure used to determine compatibility of a donor's blood with that of a recipient after the specimens have been matched for major blood type. Serum from the donor's blood is mixed with red cells from the recipient's blood, and cells from the donor are mixed with serum from the recipient. If agglutination occurs, an antigenic substance is present and the bloods are not compatible. If no agglutination occurs, the donor's blood may safely be transfused to the recipient. Compare blood typing. See also ABO blood group, Rh factor, transfusion, transfusion reaction.

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