crossmatching


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crossmatching

 [kros´mach´ing]
a procedure vital in blood transfusions and organ transplantation. The recipient's erythrocytes or leukocytes are incubated with the donor's serum and vice versa. Various testing procedures are then performed to ensure that the donor and recipient have blood group compatibility or histocompatibility. Also written cross matching and cross-matching.

crossmatching

/cross·match·ing/ (-mach-ing) determination of the compatibility of the blood of a donor and that of a recipient before transfusion by placing the donor's cells in the recipient's serum and the recipient's cells in the donor's serum; absence of agglutination, hemolysis, and cytotoxicity indicates compatibility.

crossmatching

Etymology: L, crux + AS, gemaecca, matching
a procedure in blood transfusions and organ transplantation. The recipient's erythrocytes or leukocytes are incubated with the donor's serum and vice versa. Various testing procedures are then performed to ensure that the donor and recipient have blood group compatibility or histocompatibility. Compare blood typing. See also ABO blood group, Rh factor, transfusion, transfusion reaction.

crossmatching

1. The process of mixing a sample of the donor's red blood cells with the recipient's serum (major crossmatching) and mixing a sample of the recipient's blood with the donor's serum (minor crossmatching). It is done before transfusion to determine compatibility of blood.
2. The determination of the compatibility of a donated organ's human leukocyte antigens with the recipient's antigens.
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References in periodicals archive ?
The process of pretransfusion compatibility testing involves many steps: receipt of orders for testing, sample acceptability criteria review, ABO grouping, rhesus (Rh) typing, red cell antibody screening, unexpected antibody identification, selection of appropriate donor red blood cell units, and, for some patients, crossmatching with the unit to be transfused.
Tenders are invited for supply, installation and commissioning of a brand new fully automated grouping crossmatching machine in the transfusion medicine department of regional cancer centre on reagent rental basis
Blood Group Genotyping PCR, PCR-RFLP, AS-PCR or PCR-SSP, Multiplex PCR, Real Time PCR, Sanger DNA Sequencing, Pyrosequencing Microarrays BeadChip Array, BloodChip, Genome Lab SNP Stream, Fluidic Microarray Systems, TaqMan OpenArray, MALDI-TOF-MS, Mini-Sequencing Blood Typing and Grouping Tests ABO, Antibody Panels, Antibody Screening/Indirect Antiglobulin, Antigen Typing (C, c, Duffy, E, e, I, i, Kell, Kidd, Le a, b, MN, P, S, s), Antiglobulin (Direct, C3 + IgG, IgG, C3), Crossmatching (Immediate Spin, Full Crossmatch), Rh (D, Du).
The laboratory was the single department responsible for the largest proportion of these errors, including labeling mistakes; patient or specimen misidentification; incorrect grouping, crossmatching, or antibody identification; and clerical erros.
Strictly speaking, that's true, but at least we have eliminated our old problem of equating the terms compatibility testing and crossmatching.
One screen combines the most frequently performed test-ABO/Rh, antibody screen, and direct Coombs-for crossmatching of up to 12 units.
There is no loss of "pigtails" from repetitive crossmatching.
Step Comments Pretransfusion Sample collection Correct patient Proper technique Tube identification Two unique patient identifiers Date and time of collection Laboratory testing ABO Rh Antibody screen Crossmatching Issuing of blood Physicians Order appropriate product Nurses Correctly request what was ordered Transfusion service Prepare product as ordered (i.
The ABS2000 is the only FDA cleared instrument which performs ABO grouping, Rh typing, antibody screening and crossmatching.
In other words, we were crossmatching as many as 3 units of blood for each unit actually transfused.
This could be possible since PHER-O2 does not require refrigeration nor type and crossmatching, which is necessary with packed red cells.
Eliminating routine work via instrumentation or electronic crossmatching frees up the technologist's time to focus on time-sensitive emergency situations, difficult patient workups and, eventually, the establishment of quality improvement processes.