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Crossmatch |
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Crossmatch A laboratory test done to confirm that blood from a donor and blood from the recipient are compatible. Mentioned in: Blood Typing and Crossmatching, Heart Transplantation crossmatch Serologic crossmatch Transfusion medicine An agglutination test that determines donor-recipient blood compatibility. See Electronic crossmatch, Immediate spin crossmatch, Major crossmatch, Minor crossmatch.
Crossmatch
Major crossmatch Patient serum–which may contain antibodies is cross-reacted against the donor's red cells and
Minor crossmatch Patient RBCs are incubated with donor serum, this is of less clinical significance; it reveals donor antibodies against uncommon antigens–eg Cw, -Wra, -Lia
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All patients should have their platelet counts, international normalised ratio, activated partial thromboplastin time, and bleeding time checked preoperatively, and they should be crossmatched for adequate quantities of red blood cells and platelets. Thus, the advantage of this policy for us is that identification remains the same during the period of hospitalization, and previously crossmatched units within 72-hour periods are not required to be re-crossmatched with the new sample unless an unexpected red-cell antibody is detected. Transfusion management of patients with alloimmune refractoriness involves strategies to select HLA-matched or crossmatched platelets for transfusion or to avoid crossreactive HLA or platelet antigens. |
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