cross-reaction

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cross-reaction

 [kros´re-ak-shun]
an interaction between an antibody and an antigen closely related to the antigen that specifically stimulated synthesis of the antibody.

cross-re·ac·tion

antibodies evoked by antigens with shared or similar idiotypic determinants may bind or cross-react with each other's respective antigens, even if their antigen-specificity is not identical.

cross-reaction

(krôs′rē-ăk′shən, krŏs′-)
n.
The reaction between an antigen and an antibody that was generated against a different but similar antigen.

cross′-re·act′ v.
cross′-re·ac′tive adj.
cross′-re·ac·tiv′i·ty n.

cross-reaction

Immunology A partial reaction or 'recognition' of an epitope by an antibody generated in response to another antigen

cross-re·ac·tion

(kraws'rē-ak'shŭn)
A specific reaction between an antiserum and an antigen complex other than the antigen complex that evoked the various specific antibodies of the antiserum. It is due to at least one antigenic determinant that is included among the determinants of the other complex.

cross-reaction

The association of an ANTIBODY with an ANTIGEN that differs from the antigen that first stimulated the production of the antibody. Cross reaction is unlikely unless there is close chemical similarity between the two antigens. Some diseases are believed to result because of antigenic similarities between certain body tissues and parts of infecting organisms, such as STREPTOCOCCI.

Cross-reaction

A reaction that occurs in blood testing when a disease agent reacts to the specific antibody for another disease agent. Cross-reactions are common in blood tests for fluke infections because the different species are closely related.

cross-reaction

a reaction which occurs when surface antigenic determinants on different molecules of quite different sources are identical, so that antibody directed against one antigen also reacts with another.
References in periodicals archive ?
The three companies were formed on the principle that a best-in-class source of native soluble HLA proteins would contribute to setting industry standards for cross-reactive antibody screening; and to modulating and understanding autoimmune, transplant, pathogen, and vaccine derived immune responses.
Also, the highest cross-reactive response to the H5N8 strain was observed after vaccination with 108 PFU (Figure, panel A) of MVA-H5.
Gluten-Associated Cross-Reactive Foods and Food Sensitivity Rye, Barley, Spelt, Polish Wheat Sorghum IgG + IgA Combined IgG + IgA Combined Cow's Milk IgG + IgA Combined Millet IgG + IgA Combined Alpha-Casein & Beta-Casein Hemp IgG + IgA Combined IgG + IgA Combined Casomorphin IgG + IgA Combined Amaranth IgG + IgA Combined Milk Butyrophilin IgG + IgA Combined Quinoa IgG + IgA Combined Whey Protein IgG + IgA Combined Tapioca IgG + IgA Combined Chocolate (Milk) IgG + IgA Combined Teff IgG + IgA Combined Oats IgG + IgA Combined Soy IgG + IgA Combined Yeast IgG + IgA Combined Egg IgG + IgA Combined Coffee IgG + IgA Combined Corn IgG IgA Combined Sesame IgG + IgA Combined Rice IgG + IgA Combined Buckwheat IgG + IgA Combined Potato IgG + IgA Combined
University, and the University of Aarhus (Denmark) tested 500 pregnant Danish women for antibodies to a human hsp6o that was cross-reactive with a bacterial hsp.
writes that such cross-reactive CTLs "may suffice to protect [humans] against at least low-level exposure to a variety [of AIDS virus strains].
Fischer, lead author of #1014, "Targeting cancer stem cells by a Notch 2/Notch3 cross-reactive antibody inhibits tumor growth and delays tumor recurrence in pancreatic cancer", presented new data demonstrating that OncoMed's anti-Notch2/3 antibody OMP-59R5 was active both as a single agent and in combination with gemcitabine in a panel of patient-derived pancreatic xenografts.
03: Characterization of cross-reactive T-cell receptors that recognize both Epstein Barr virus and influenza A virus during acute influenza A virus infection Presenter: InYoung Song, University of Massachusetts Medical School Time: Sunday, May 10, 2015, 2:30-3:45pm
It is unknown if these antibodies reflect previous exposure to pH1N1 virus or are reflective of cross-reactive antibodies generated against antigenic sites in previously circulating influenza viruses.
The kind of antibody studied is called a broadly cross-reactive neutralizing antibody, and details of its generation could provide a blueprint for effective vaccination, the study's researchers said.
Patients who have not responded to the removal of gluten from their diet often benefit from testing for sensitivity to cross-reactive foods.
Clinical trials show that these vaccines do offer some cross-reactive protection against virus strains 31 and 45.
In pre-clinical studies, HuMax-HepC was shown to be broadly cross-reactive with several HCV genotypes and potently neutralized binding of HCV-E2 to susceptible cells.