cross-reaction


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cross-reaction

 [kros´re-ak-shun]
an interaction between an antibody and an antigen closely related to the antigen that specifically stimulated synthesis of the antibody.

cross-re·ac·tion

antibodies evoked by antigens with shared or similar idiotypic determinants may bind or cross-react with each other's respective antigens, even if their antigen-specificity is not identical.

cross-reaction

(krôs′rē-ăk′shən, krŏs′-)
n.
The reaction between an antigen and an antibody that was generated against a different but similar antigen.

cross′-re·act′ v.
cross′-re·ac′tive adj.
cross′-re·ac·tiv′i·ty n.

cross-reaction

Immunology A partial reaction or 'recognition' of an epitope by an antibody generated in response to another antigen

cross-re·ac·tion

(kraws'rē-ak'shŭn)
A specific reaction between an antiserum and an antigen complex other than the antigen complex that evoked the various specific antibodies of the antiserum. It is due to at least one antigenic determinant that is included among the determinants of the other complex.

cross-reaction

The association of an ANTIBODY with an ANTIGEN that differs from the antigen that first stimulated the production of the antibody. Cross reaction is unlikely unless there is close chemical similarity between the two antigens. Some diseases are believed to result because of antigenic similarities between certain body tissues and parts of infecting organisms, such as STREPTOCOCCI.

Cross-reaction

A reaction that occurs in blood testing when a disease agent reacts to the specific antibody for another disease agent. Cross-reactions are common in blood tests for fluke infections because the different species are closely related.

cross-reaction

a reaction which occurs when surface antigenic determinants on different molecules of quite different sources are identical, so that antibody directed against one antigen also reacts with another.
References in periodicals archive ?
As proven by specificity testing including triplicate measurements, none of the 5 individual assays developed for the identification of DOBV, PUUV, TULV, HNTV/SEOV, and ANDV/SNV showed nonspecific cross-reactions to other hantaviruses.
The rabbit antiserum initially exhibited a weak but recognizable cross-reaction to the somatic tissues in the double immuno-diffusion test.
The mildly high Echinococcus granulosus IHA was considered to be a cross-reaction with Fasciola hepatica.
Latex-sensitive individuals should avoid these fruits, vegetables, and nuts because they may create an allergic cross-reaction.
2) After previous studies performed in eastern Colombia on T cruzi infection, (3) we found a new cross-reaction for HIV that had never been described before.
Soy protein could cause a cross-reaction to peanut protein, which has a similar chemical structure, the authors speculated.
And the transsexual said that the incident sparked a cross-reaction on her part.
One was correctly identified, but also elicited a cross-reaction to mouse antiserum.
The NPC-1C epitope appears to be a variant of MUC5AC that is expressed specifically by human colon and pancreatic tumor tissues and cell lines with only minimal and weak cross-reaction occasionally to certain GI tract tissues.
Cross-reaction of immune sera from patients with rickettsial diseases.
Fenugreek gives a stronger cross-reaction to peanut than other legumes.