cross tolerance

cross tolerance

n.

Resistance to an effect or effects of a compound as a result of tolerance previously developed to a pharmacologically similar compound.

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tolerance (tol´rns),

n the ability to endure the influence of a drug or poison, particularly acquired by continued use of the substance. See also resistance.

tolerance, acquired,

n tolerance that develops with successive doses of a drug. If it develops within a short span of time, such as 24 hours, it is called
tachyphylaxis. Slowly acquired tolerance is sometimes called
mithridatism.

tolerance, carbohydrate,

n the ability of the body to use carbohydrates. A decrease in tolerance is seen in diabetes mellitus, liver damage, and some infections and in the presence of hyperactivity of the adrenal cortex or pituitary gland.

tolerance, cross,

n tolerance to a number of drugs of similar mode of action or chemical structure.

tolerance, individual,

n tolerance characteristic of an individual.

tolerance, pseudo-,

n a state of apparent tolerance indicated due to failure of the drug to reach its usual receptor sites.

tolerance, species,

n tolerance characteristic of a species of animal.

tolerance, tissue,

n the ability of structures to endure environmental change without ill effect.

tolerance, upper intake level,

n the specified limit of a given substance that an individual may consume and not suffer detrimental or toxic effects.