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Cromolyn sodium does not operate through the cyclic adenosine 3',5'-monophosphate (cAMP) system and does not affect alpha or beta receptors.
Our previous work showing that cromolyn sodium can block toxin-induced constrictor effects (Abraham et al.
Stabilization of the mast cells by cromolyn sodium and the antihistamine effects of loratadine and ranitidine may account for this regimen's effectiveness if indeed mast cell dysfunction is involved in the development of the syndrome.
Cromolyn sodium for asthma and extended-release antihistamines will drive up regional demand for bulk respiratory agents.
There are also new nasal sprays: internasal steroids, internasal antihistamines, and anti-inflammatory or mast cell blockers, such as cromolyn sodium, which block the allergic reaction.
Cromolyn sodium, 2 puffs 15 to 20 minutes before exercise, is also effective and may have particular benefit in patients with atopic disease.
Use cromolyn sodium nasal spray before engaging in outdoor activities, such as mowing the grass, gardening, or playing golf or soccer.
As with cromolyn sodium, nedocromil sodium is indicated as prophylactic therapy in the management of asthma.
Cromolyn sodium is considered an anti-asthmatic, an antiallergic and a mast cell stabilizer.
Emisphere and its partners have advanced oral formulations or prototypes of salmon calcitonin, heparin, insulin, parathyroid hormone, human growth hormone and cromolyn sodium into clinical trials.
Cromolyn sodium is an anti-inflammatory agent that helps stabilize the surface membranes of eosinophils and mast cells.
AlphaMed's product pipeline includes AAT for pulmonary and dermatological use as well as cromolyn sodium for a variety of topical indications.