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cromolyn

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cromolyn /cro·mo·lyn/ (kro´mol-in) an inhibitor of the release of histamine and other mediators of immediate hypersensitivity from mast cells; used as the sodium salt for prophylaxis and treatment of allergic rhinitis, bronchial asthma associated with allergy, and allergen-induced inflammation of the conjunctiva or cornea, and for treatment of mastocytosis.
cromolyn [kro´mŏ-lin]
a drug that inhibits the release of chemical mediators of immediate sensitivity from basophils and mast cells, administered by inhalation or intranasally for prophylaxis and treatment of bronchial asthma and allergic rhinitis, orally for treatment of mastocytosis, and topically to the conjunctiva for prevention and treatment of allergen-induced inflammation of the conjunctiva or cornea. It has the advantage of reducing or eliminating the need for steroids and sympathomimetics. Used in the form of its disodium salt, cromolyn sodium.

cromolyn
a mast cell stabilizer which, if administered prior to exposure to allergens, prevents degranulation and release of histamine in a hypersensitivity reaction. Administered as an aerosol for prophylaxis of bronchial asthma and allergic rhinitis. Investigated for use in the treatment of chronic obstructive pulmonary disease in horses. Called also cromoglycate.


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Cromolyn sodium is a nasal spray that helps prevent the body's reaction to allergens.
We knew from published research that both cromolyn and Zaditor help stabilize mast cells in people suffering from allergy or asthma," said Nature magazine quoted Shi as saying.
In a study published in the journal Nature Medicine, his team tried out two common over-the-counter allergy drugs, ketotifen fumarate and cromolyn, on lab mice that were obese and diabetic.
 
 
 
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