cromolyn


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Related to cromolyn: cromolyn sodium

cromolyn

 [kro´mŏ-lin]
a drug that inhibits the release of chemical mediators of immediate sensitivity from basophils and mast cells, administered by inhalation or intranasally for prophylaxis and treatment of bronchial asthma and allergic rhinitis, orally for treatment of mastocytosis, and topically to the conjunctiva for prevention and treatment of allergen-induced inflammation of the conjunctiva or cornea. It has the advantage of reducing or eliminating the need for steroids and sympathomimetics. Used in the form of its disodium salt, cromolyn sodium.

cromolyn

/cro·mo·lyn/ (kro´mol-in) an inhibitor of the release of histamine and other mediators of immediate hypersensitivity from mast cells; used as the sodium salt for prophylaxis and treatment of allergic rhinitis, bronchial asthma associated with allergy, and allergen-induced inflammation of the conjunctiva or cornea, and for treatment of mastocytosis.

cromolyn

(krō′mə-lĭn)
n.
A drug, C23H16O11, given in the form of its sodium salt, that inhibits the release of histamine from mast cells and is used as an inhalant or topically in the treatment of allergies and to prevent asthmatic attacks.

cromolyn

a mast cell stabilizer which, if administered prior to exposure to allergens, prevents degranulation and release of histamine in a hypersensitivity reaction. Administered as an aerosol for prophylaxis of bronchial asthma and allergic rhinitis. Investigated for use in the treatment of chronic obstructive pulmonary disease in horses. Called also cromoglycate.
References in periodicals archive ?
Cromolyn prevents the extrusion of granules containing the mediators of inflammation.
Mice fed a healthy diet improved moderately, while those given either cromolyn or Zaditor showed dramatic improvements.
We knew from published research that both cromolyn and Zaditor help stabilize mast cells in people suffering from allergy or asthma," said Nature magazine quoted Shi as saying.
Alternative -- Cromolyn, leukotriene receptor antagonist, or theophylline (serum level 5-12 mcg/mL).
Our previous work showing that cromolyn sodium can block toxin-induced constrictor effects (Abraham et al.
Cromolyn sodium, nedocromil sodium and corticosteroids are examples of anti-inflammatory medications currently available to treat asthma.
Before testing, the patient should refrain from use of short-acting beta agonists for 6 hours and leukotriene inhibitors, long-acting beta agonists, and cromolyn for 24 hours.
Antihistamines, decongestants, intranasal steroids and cromolyn are effective.
Use cromolyn sodium nasal spray before engaging in outdoor activities, such as mowing the grass, gardening, or playing golf or soccer.
Medicines such as albuterol or cromolyn by inhalation can help prevent wheezing.
Cromolyn sodium for asthma and extended-release antihistamines will drive up regional demand for bulk respiratory agents.
These medicines include inhaled steroids, cromolyn, and nedocromil.