critical organ

crit·i·cal or·gan

the organ or physiologic system that for a given source of radiation would first reach its legally defined maximum permissible radiation exposure as the dose of radiation is increased; for example, the kidney is the critical organ, receiving the most radiation, when Tc-99m dimethylsuccinic acid is given.

crit·i·cal or·gan

(krit'i-kăl ōr'găn)
The organ or physiologic system that for a given source of radiation would first reach its legally defined maximum permissible radiation exposure as the dose of radiopharmaceutical is increased.
References in periodicals archive ?
22) Based on this and other preclinical work, possible SBRT doses include 30 to 45 Gy in 3 to 5 fractions depending on critical organ tolerance and risk of toxicity (Table 2).
Soliris can be a breakthrough treatment for some patients not only controlling symptoms and the severity of attacks, but it can restore critical organ function and in some patients can have the effect of putting the disease into remission.
Other risk factors of hypoglycemia include alcohol, critical organ failure (kidney, heart, or liver), drug interactions with other medications, critical illness, hormone deficiencies and tumors
Bleeding was considered major if it was fatal, occurred in a critical organ, or was associated with a decrease in hemoglobin of greater than 2.
Bleeding into a critical organ was reduced by 31%, while the risk of fatal bleeding was cut in half.
Doctors had to restart his heart twice within ten minutes of him being born and in the following days he suffered critical organ failure.
To close this gap, the following broad areas of research topics need attention: a) better health tracking and monitoring data for chronic diseases, b) more comprehensive and longitudinal biomonitoring of environmental agents that can be linked with specific molecular/biochemical markers of exposure and subsequent health outcome data, and c) more epidemiologic research and testing of environmental agents to better define their effects on the adult and developing brain, as well as other critical organ systems.
Childhood is a period of critical organ development and fast growth.
Within days, there follows critical organ failure and the skin around the infected area turns black.
Critical organ transplants are a major risk with self-insured medical plans.
Providing a complete and multidisciplinary overview of the gastrointestinal system both in health and as it is involved in the toxicity of exogenous agents, Toxicology of the Gastrointestinal Tract brings together the current and growing knowledge of this critical organ system in a single volume.
Both diseases are caused by an enzyme deficiency and can cause critical organ damage and death.

Full browser ?