cretinism /cre·tin·ism/ (kre´tin-izm) arrested physical and mental development with dystrophy of bones and soft tissues, due to congenital lack of thyroid secretion.
Cretinism
cretinism
cretinism (krē´t
nizm) (congenital hypothyroidism),
athyrotic cretinism cretinism due to thyroid aplasia or destruction of the thyroid of the fetus in utero.
endemic cretinism a form occurring in regions of severe endemic goiter, marked by deaf-mutism, spasticity, and motor dysfunction in addition to, or instead of, the usual manifestations of cretinism.
sporadic goitrous cretinism a genetic disorder in which enlargement of the thyroid gland is associated with deficient circulating thyroid hormone.
cre·tin·ism (kr t n- z  m)n. A congenital condition due to thyroid hormone deficiency during fetal development and marked in childhood by dwarfed stature, mental retardation, dystrophy of the bones, and a low basal metabolism. Also called congenital myxedema, cretinoid dysplasia. |
Cretinism
Severe hypothyroidism that is present at birth and characterized by severe mental retardation.
Mentioned in: Hypothyroidism, Thyroid Function Tests
cretinism
[krē′təniz′əm]
Etymology: Fr, cretin, idiot
a congenital condition characterized by severe hypothyroidism and often associated with other endocrine abnormalities. Myxedema is the acquired form of hypothyroidism. Typical signs of cretinism include dwarfism, mental deficiency, puffy facial features, dry skin, large tongue, umbilical hernia, and muscular incoordination. The disorder occurs usually in areas where the diet is deficient in iodine and where goiter is common. Early treatment with thyroid hormone generally promotes normal physical growth but may not prevent mental retardation. The use of iodized salt dramatically reduces the incidence of cretinism in a population. The condition is rare in the United States, but in some areas, including parts of Ecuador, the Himalayas, and Zaire, more than 5% of the people are affected. See also familial cretinism. cretin, n., cretinous, adj.
cretinism (krē´t
nizm) (congenital hypothyroidism),n See hypothyroidism.
cretinism
arrested physical and mental development with dystrophy of bones and soft tissues, resulting in disproportionate dwarfism. Due to congenital or early-onset hypothyroidism. Seen in foals and possibly is an unrecognized cause of neonatal deaths in other species.
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